Desorption electrospray ionization mass spectrometry for lipid characterization and biological tissue imaging.
Desorption electrospray ionization mass spectrometry for lipid characterization and biological tissue imaging.
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DOI:
10.1016/j.bbalip.2011.05.006
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发表时间:
2011-11
期刊:
影响因子:
--
通讯作者:
Cooks RG
中科院分区:
文献类型:
--
作者:
Eberlin LS;Ferreira CR;Dill AL;Ifa DR;Cooks RG
Desorption electrospray ionization mass spectrometry (DESI-MS) imaging of biological samples allows untargeted analysis and structural characterization of lipids ionized from the near-surface region of a sample under ambient conditions. DESI is a powerful and sensitive MS ionization method for 2D and 3D imaging of lipids from direct and unmodified complex biological samples. This review describes the strengths and limitations of DESI-MS for lipid characterization and imaging together with the technical workflow and a survey of applications. Included are discussions of lipid mapping and biomarker discovery as well as a perspective on the future of DESI imaging.
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影响因子:
7.4
作者:
Beljebbar, Abdelilah;Dukic, Sylvain;Manfait, Michel
通讯作者:
Manfait, Michel
DOI:
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发表时间:
2008-07-15
影响因子:
3
作者:
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Yamaguchi, Seiji
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4.9
作者:
Chen, H;Cotte-Rodríguez, I;Cooks, RG
通讯作者:
Cooks, RG
影响因子:
7.4
作者:
Eberlin, Livia S.;Dill, Allison L.;Costa, Anthony B.;Ifa, Demian R.;Cheng, Liang;Masterson, Timothy;Koch, Michael;Ratliff, Timothy L.;Cooks, R. Graham
通讯作者:
Cooks, R. Graham
DOI:
10.1146/annurev.anchem.111808.073705
发表时间:
2010-01-01
期刊:
ANNUAL REVIEW OF ANALYTICAL CHEMISTRY, VOL 3
影响因子:
--
作者:
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通讯作者:
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