Zika, Chikungunya, and Other Emerging Vector-Borne Viral Diseases.

Zika, Chikungunya, and Other Emerging Vector-Borne Viral Diseases.
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DOI:
10.1146/annurev-med-050715-105122
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发表时间:
2018-01-29
影响因子:
10.5
通讯作者:
Lecuit M
Lecuit M
中科院分区:
医学1区
文献类型:
--
作者:
Weaver SC;Charlier C;Vasilakis N;Lecuit M

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节肢动物传播的病毒(虫媒病毒)感染人类的历史很长,但在最近几十年里,它们已经传播得更广泛,影响了更大的人群。这是由几个因素造成的,包括航空旅行的增加和不受控制的蚊媒种群。出现可能涉及地方病(野生动物)周期的简单溢出,例如西尼罗河病毒伴随地理扩张到美洲的情况;家养动物中的二次扩增,例如日本脑炎、委内瑞拉马脑炎和裂谷热病毒;和城市化,其中人类成为扩增宿主,居住区蚊子(主要是埃及伊蚊)介导人与人的传播。登革热、黄热病、基孔肯雅热和寨卡病毒都经历了这样的城市出现。我们主要关注后两种,它们是最近到达西半球的。我们还讨论了其他几种有可能通过所有这些机制出现的病毒。
Arthropod-borne viruses (arboviruses) have a long history of emerging to infect humans, but during recent decades, they have been spreading more widely and affecting larger populations. This is due to several factors, including increased air travel and uncontrolled mosquito vector populations. Emergence can involve simple spillover from enzootic (wildlife) cycles, as in the case of West Nile virus accompanying geographic expansion into the Americas; secondary amplification in domesticated animals, as seen with Japanese encephalitis, Venezuelan equine encephalitis, and Rift Valley fever viruses; and urbanization, in which humans become the amplification hosts and peridomestic mosquitoes, mainly Aedes aegypti, mediate human-to-human transmission. Dengue, yellow fever, chikungunya, and Zika viruses have undergone such urban emergence. We focus mainly on the latter two, which are recent arrivals in the Western Hemisphere. We also discuss a few other viruses with the potential to emerge through all of these mechanisms.
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