Schwann cells and trigeminal neuralgia.
Schwann cells and trigeminal neuralgia.
复制标题
雪旺细胞和三叉神经痛。
DOI:
10.1177/1744806920963809
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发表时间:
2020-01
期刊:
影响因子:
3.3
通讯作者:
Liu ZX
中科院分区:
文献类型:
--
作者:
Liao JY;Zhou TH;Chen BK;Liu ZX
Schwann cells are components of the peripheral nerve myelin sheath, which supports and nourishes axons. Upon injury of the trigeminal nerve, Schwann cells are activated and cause trigeminal neuralgia by engulfing the myelin sheath and secreting various neurotrophic factors. Further, Schwann cells can repair the damaged nerve and thus alleviate trigeminal neuralgia. Here, we briefly describe the development and activation of Schwann cells after nerve injury. Moreover, we expound on the occurrence, regulation, and treatment of trigeminal neuralgia; further, we point out the current research deficiencies and future research directions.
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