Association of sedentary time with mortality independent of moderate to vigorous physical activity.
Association of sedentary time with mortality independent of moderate to vigorous physical activity.
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DOI：
10.1371/journal.pone.0037696
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发表时间：
2012
期刊：
影响因子：
3.7
通讯作者：
Harris TB
中科院分区：
文献类型：
--
作者：
Koster A;Caserotti P;Patel KV;Matthews CE;Berrigan D;Van Domelen DR;Brychta RJ;Chen KY;Harris TB
久坐行为已经成为一种新的健康风险因素，独立于中度到剧烈的体力活动（MVPA）。先前的研究表明，自我报告的久坐时间与死亡率相关;然而，没有研究调查客观测量的久坐时间对死亡率的影响，而不依赖于MVPA。我们的研究目的是检查客观测量的久坐时间和全因死亡率之间的关系。7-分析了2003-2004年美国全国代表性国家健康和营养调查（NHANES）中1906名50岁及以上参与者的日加速度测量数据。评估了从检查之日至2006年12月31日的全因死亡率。在平均2.8年的随访中，报告了145例死亡。在一个调整了社会人口因素、生活方式因素、多种疾病、活动受限和MVPA的模型中，与最低四分位数的参与者相比，久坐时间百分比较高的第三四分位数（风险比（HR）：4.05; 95%CI：1.55-10.60）和第四四分位数（HR：5.94; 95%CI：2.49-14.15）的参与者死亡风险显著增加。我们的研究表明，久坐行为是独立于MVPA的死亡率危险因素。需要进一步的调查，包括更长时间的随访研究，以解决久坐行为的健康后果。
Sedentary behavior has emerged as a novel health risk factor independent of moderate to vigorous physical activity (MVPA). Previous studies have shown self-reported sedentary time to be associated with mortality; however, no studies have investigated the effect of objectively measured sedentary time on mortality independent of MVPA. The objective our study was to examine the association between objectively measured sedentary time and all-cause mortality. 7-day accelerometry data of 1906 participants aged 50 and over from the U.S. nationally representative National Health and Nutrition Examination Survey (NHANES) 2003–2004 were analyzed. All-cause mortality was assessed from the date of examination through December 31, 2006. Over an average follow-up of 2.8 years, there were 145 deaths reported. In a model adjusted for sociodemographic factors, lifestyle factors, multiple morbidities, mobility limitation, and MVPA, participants in third quartile (hazard ratio (HR):4.05; 95%CI:1.55–10.60) and fourth quartile (HR:5.94; 95%CI: 2.49–14.15) of having higher percent sedentary time had a significantly increased risk of death compared to those in the lowest quartile. Our study suggests that sedentary behavior is a risk factor for mortality independent of MVPA. Further investigation, including studies with longer follow-up, is needed to address the health consequences of sedentary behavior.
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影响因子：
5
作者：
Matthews, Charles E.;Chen, Kong Y.;Troiano, Richard P.
通讯作者：
Troiano, Richard P.
影响因子：
7.7
作者：
Hamilton, Marc T.;Hamilton, Deborah G.;Zderic, Theodore W.
通讯作者：
Zderic, Theodore W.
影响因子：
16.2
作者：
Bankoski A;Harris TB;McClain JJ;Brychta RJ;Caserotti P;Chen KY;Berrigan D;Troiano RP;Koster A
通讯作者：
Koster A
影响因子：
5
作者：
Patel, Alpa V.;Bernstein, Leslie;Thun, Michael J.
通讯作者：
Thun, Michael J.
影响因子：
120.7
作者：
Kujala, UM;Kaprio, J;Koskenvuo, M
通讯作者：
Koskenvuo, M