Cerebral asymmetry and language development: cause, correlate, or consequence?

Cerebral asymmetry and language development: cause, correlate, or consequence?
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DOI:
10.1126/science.1230531
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发表时间:
2013-06-14
期刊:
Science (New York, N.Y.)
影响因子:
--
通讯作者:
Bishop DV
Bishop DV
中科院分区:
其他
文献类型:
--
作者:
Bishop DV

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在大多数人中,语言主要由左半球处理,但我们不知道如何或为什么。一个流行的观点是,发育性语言障碍是由大脑侧化不良造成的,但直到最近,证据一直很薄弱和间接。现代神经影像学方法使研究发育中大脑的正常和异常侧化功能发展成为可能,并证实了与语言和识字障碍的联系。然而,很少有证据表明,弱大脑侧化与语言/识字障碍有共同的遗传起源。如果我们重新概念化大脑不对称的性质,以认识其多维性质,并考虑到在发展时间的偏侧化的变化,我们的理解之间的关联非典型语言偏侧化和发育障碍可能会受益。与流行的观点相反,大脑侧化可能不是一个高度遗传的,稳定的个体特征;相反,弱侧化可能是语言学习受损的结果。
In most people language is processed predominantly by the left hemisphere, but we don’t know how or why. A popular view is that developmental language disorders result from a poorly lateralized brain, but until recently evidence has been weak and indirect. Modern neuroimaging methods have made it possible to study normal and abnormal development of lateralized function in the developing brain and have confirmed links with language and literacy impairments. However, there is little evidence that weak cerebral lateralization has common genetic origins with language/literacy impairments. Our understanding of the association between atypical language lateralization and developmental disorders may benefit if we reconceptualise the nature of cerebral asymmetry to recognize its multidimensional nature and to take into account variation in lateralization over developmental time. Contrary to popular belief, cerebral lateralization may not be a highly heritable, stable characteristic of individuals; rather, weak lateralization may be a consequence of impaired language learning.
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