Localization of language-specific cortex by using magnetic source imaging and electrical stimulation mapping.
Localization of language-specific cortex by using magnetic source imaging and electrical stimulation mapping.
复制标题
使用磁源成像和电刺激映射对语言特定皮层进行定位。
作者：
P. Simos;Andrew C. Papanicolaou;J. Breier;James W. Wheless;J. Constantinou;William B. Gormley;W. Maggio
对象
在本文中，作者证明了磁源(MS)成像和直接皮质刺激在标测接受性语言皮质方面的一致性。
方法
在连续13名手术患者中，通过在视觉和听觉单词识别任务的背景下，通过MS成像辅助获得激活图，非侵入性地识别了专门负责接受性语言功能的皮质。手术治疗难治性癫痫(8例)，切除肿瘤(4例)或血管瘤(1例)。术中10名患者和术外3名患者进行了皮质刺激下的语言区域标测。皮质刺激标测证实了所有病例基于MS成像定位的准确性。
结论
MS成像提供的信息对于非典型语言表达的情况尤其有用，包括双半球表征，以及语言在优势半球内预期区域以外的区域的位置，如颞上回的前部、颞中回的后下部、颞底皮质和外侧颞枕叶皮质。
OBJECT
In this paper the authors demonstrate the concordance between magnetic source (MS) imaging and direct cortical stimulation for mapping receptive language cortex.
METHODS
In 13 consecutive surgical patients, cortex specialized for receptive language functions was identified noninvasively by obtaining activation maps aided by MS imaging in the context of visual and auditory word-recognition tasks. Surgery was then performed for treatment of medically intractable seizure disorder (eight patients), and for resection of tumor (four), or angioma (one). Mapping of language areas with cortical stimulation was performed intraoperatively in 10 patients and extraoperatively in three. Cortical stimulation mapping verified the accuracy of the MS imaging-based localization in all cases.
CONCLUSIONS
Information provided by MS imaging can be especially helpful in cases of atypical language representation, including bihemispheric representation, and location of language in areas other than those expected within the dominant hemisphere, such as the anterior portion of the superior temporal gyrus, the posteroinferior portion of the middle temporal gyrus, the basal temporal cortex, and the lateral temporooccipital cortex.
影响因子：
4.1
作者：
OJEMANN, G;OJEMANN, J;BERGER, M
通讯作者：
BERGER, M
使用脑磁图评估语言的功能性大脑偏侧性。
DOI：
10.1097/00004691-199807000-00009
发表时间：
1998
期刊：
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.
影响因子：
--
作者：
Simos,PG;Breier,JI;Zouridakis,G;Papanicolaou,AC
通讯作者：
Papanicolaou,AC
DOI：
10.1073/pnas.95.5.2636
发表时间：
1998-03-03
影响因子：
11.1
作者：
Shaywitz, SE;Shaywitz, BA;Gore, JC
通讯作者：
Gore, JC