Epidemiology of pancreatic cancer.
Epidemiology of pancreatic cancer.
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DOI：
10.3748/wjg.v22.i44.9694
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发表时间：
2016-11-28
影响因子：
4.3
通讯作者：
Ilic I
中科院分区：
文献类型：
--
作者：
Ilic M;Ilic I
胰腺癌仍然是最致命的癌症类型之一。根据GLOBOCAN 2012年的估计，胰腺癌每年导致超过331000人死亡，在男性和女性中均为第七大癌症死亡原因。2012年，全球约有33.8万人患有胰腺癌，使其成为第11大常见癌症。胰腺癌的发病率和死亡率最高的是发达国家。世界各地胰腺癌发病率和死亡率的趋势差异很大。胰腺癌的一个已知原因是吸烟。这一风险因素可能解释了一些国际差异和性别差异。总体五年生存率约为6%（范围从2%到9%），但发达国家和发展中国家之间的差异非常小。迄今为止，胰腺癌的原因仍然不充分，尽管已经确定了某些风险因素，如吸烟，肥胖，遗传，糖尿病，饮食，不活动。目前还没有胰腺癌的筛查建议，因此一级预防至关重要。更好地了解病因和识别危险因素对于这种疾病的一级预防至关重要。
Cancer of the pancreas remains one of the deadliest cancer types. Based on the GLOBOCAN 2012 estimates, pancreatic cancer causes more than 331000 deaths per year, ranking as the seventh leading cause of cancer death in both sexes together. Globally, about 338000 people had pancreatic cancer in 2012, making it the 11th most common cancer. The highest incidence and mortality rates of pancreatic cancer are found in developed countries. Trends for pancreatic cancer incidence and mortality varied considerably in the world. A known cause of pancreatic cancer is tobacco smoking. This risk factor is likely to explain some of the international variations and gender differences. The overall five-year survival rate is about 6% (ranges from 2% to 9%), but this vary very small between developed and developing countries. To date, the causes of pancreatic cancer are still insufficiently known, although certain risk factors have been identified, such as smoking, obesity, genetics, diabetes, diet, inactivity. There are no current screening recommendations for pancreatic cancer, so primary prevention is of utmost importance. A better understanding of the etiology and identifying the risk factors is essential for the primary prevention of this disease.
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影响因子：
8.8
作者：
Bao Y;Hu FB;Giovannucci EL;Wolpin BM;Stampfer MJ;Willett WC;Fuchs CS
通讯作者：
Fuchs CS
DOI：
10.1097/ppo.0000000000000109
发表时间：
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期刊：
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--
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作者：
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通讯作者：
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影响因子：
3.7
作者：
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通讯作者：
Aggarwal, Bharat B.
DOI：
10.3945/ajcn.115.119461
发表时间：
2016-01
期刊：
The American journal of clinical nutrition
影响因子：
--
作者：
Appleby PN;Crowe FL;Bradbury KE;Travis RC;Key TJ
通讯作者：
Key TJ