Age-Varying Relationships Between Physical Function and Cognition in Older Adulthood.
Age-Varying Relationships Between Physical Function and Cognition in Older Adulthood.
复制标题
老年人身体机能与认知之间随年龄变化的关系。
DOI：
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复制
发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Lesley A Ross
中科院分区：
文献类型：
--
作者：
Briana N Sprague;Christine B. Phillips;Lesley A Ross
目标
在老年人中，身体和认知功能之间存在正相关关系;然而，这些关系的强度在研究中并不一致。虽然新的统计工具提供了灵活性，探索年龄相关的关系幅度的差异，这种方法还没有在老年学研究中实施。本研究应用这些方法来检查健康老年人（N = 2，783）的身体功能和认知之间的关系幅度的变化。
方法
时变效应建模（TVEM）是回归的扩展，它将关系中的变化建模为随时间变化的指标（如年龄）的函数。TVEM用于检查身体功能（360转，握力）是否预测65-90岁成年人的认知表现（记忆，处理速度/注意力和推理）。
结果
转折360和所有认知领域之间的所有关联都是显著和积极的;然而，处理速度在不同年龄段之间有显著的幅度变化，例如，老年人和老年人表现出最强的关系。随着年龄的增长，握力和所有认知领域之间的关联显着加强。
讨论
结果表明，根据样本的年龄，可能有不一致的身体和认知性能之间的关系。未来的研究应该纵向探讨这些关系，以更好地阐明不一致的结果。
OBJECTIVES
There are positive relationships between physical and cognitive function in older adulthood; however, the strength of these relationships are inconsistent across studies. Although novel statistical tools provide flexibility to explore age-related differences in relationship magnitude, such methods have not been implemented in gerontological research. This study applied such methods to examine variations in relationship magnitude between physical function and cognition in healthy older adults (N = 2,783).
METHOD
Time-varying effects modeling (TVEM) is an extension of regression that models changes in relationships as a function of time-varying metrics like age. TVEM was used to examine if physical function (Turn 360, grip strength) predicted cognitive performance (memory, processing speed/attention, and reasoning) similarly across adults aged 65-90.
RESULTS
All associations between Turn 360 and all cognitive domains were significant and positive; however, speed of processing had significant magnitude variation across age such that the young-old and the old-old demonstrated the strongest relationships. Associations between grip strength and all cognitive domains significantly strengthened with increased age.
DISCUSSION
Results suggest that depending on the sample age, there may be inconsistencies in the relationships between physical and cognitive performance. Future research should explore these relationships longitudinally to better elucidate discrepant findings.
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DOI：
10.1097/jgp.0b013e3181ef7a2e
发表时间：
2011-06
期刊：
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
影响因子：
--
作者：
Buchman AS;Boyle PA;Leurgans SE;Barnes LL;Bennett DA
通讯作者：
Bennett DA
DOI：
10.1093/geronb/gbv017
发表时间：
2016-09-01
影响因子：
6.2
作者：
Sternang, Ola;Reynolds, Chandra A.;Aslan, Anna K. Dahl
通讯作者：
Aslan, Anna K. Dahl
DOI：
10.1093/gerona/glp075
发表时间：
2009-09-01
影响因子：
5.1
作者：
Hajjar, Ihab;Yang, Frances;Lipsitz, Lewis A.
通讯作者：
Lipsitz, Lewis A.
DOI：
10.1093/gerona/62.8.844
发表时间：
2007-08-01
影响因子：
5.1
作者：
Atkinson, Hal H.;Rosano, Caterina;Kritchevsky, Stephen B.
通讯作者：
Kritchevsky, Stephen B.
DOI：
10.1016/s0197-2456(01)00139-8
发表时间：
2001-08-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
Jobe, JB;Smith, DM;Kleinman, K
通讯作者：
Kleinman, K