A cluster of methicillin-sensitive Staphylococcus aureus colonization in a nursery
A cluster of methicillin-sensitive Staphylococcus aureus colonization in a nursery
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托儿所内一群对甲氧西林敏感的金黄色葡萄球菌定植
DOI：
10.1515/jpm.2011.114
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Shuenn
中科院分区：
文献类型：
--
作者：
Yhu;A. Chao;L. Su;Shuenn
背景：金黄色葡萄球菌是医院菌血症最重要的病原菌之一。定植菌株可能会传播给其他患者。方法：对92名到产房就诊的产妇进行调查。从母亲的鼻腔和阴道采集标本，检测金黄色葡萄球菌。在婴儿室24小时内从婴儿的鼻腔和脐部采集标本。结果：产妇携带金黄色葡萄球菌率为25%，婴儿携带金黄色葡萄球菌率为30.9%。其中以甲氧西林敏感金黄色葡萄球菌（MSSA）居多（55株，94.8%）。在55株MSSA分离株中，从母亲分离株中鉴定出11种基因型，从婴儿分离株中鉴定出5种基因型。鉴定出一个主要克隆，占34个婴儿分离株的82%。九对母亲和婴儿被MSSA定植；通过分子方法，两对分离菌株难以区分。结论：新生儿在出生后很快获得金黄色葡萄球菌定植，部分来自其母亲。一旦将金黄色葡萄球菌引入托儿所，如果卫生保健工作者不严格执行感染控制措施，则可能发生菌株传播。
Abstract Background: Staphylococcus aureus is among the most important pathogens of bacteremia in hospitals. Colonizing strains may spread to other patients. Methods: Ninety-two mothers visiting delivery rooms were included in this study. From the mothers, specimens were obtained from the nares and vagina for the detection of S. aureus. From the babies, specimens were obtained from the nares and umbilicus within 24 h in the nursery. Results: The carriage rates of S. aureus were 25% in the parturient mothers and 30.9% in their babies. The majority (55 isolates, 94.8%) of the isolates were methicillin-sensitive S. aureus (MSSA). Of the 55 MSSA isolates, 11 genotypes were identified for isolates from the mothers and five geno-types for isolates from the infants. A major clone was identified and accounted for 82% of 34 isolates from the babies. Nine pairs of mothers and babies were colonized with MSSA; by molecular methods, the paired isolates were indistinguishable in two pairs. Conclusion: Newborn babies acquire S. aureus colonization soon after birth, partly from their mothers. Once S. aureus is introduced into a nursery, spread of the strain may occur if health-care workers do not execute infection control measures strictly.
影响因子：
11.8
作者：
Lina, G;Piémont, Y;Etienne, J
通讯作者：
Etienne, J
影响因子：
9.4
作者：
Boyle-Vavra, S;Ereshefsky, B;Daum, RS
通讯作者：
Daum, RS