Normative Left Ventricular M-Mode Echocardiographic Values in Preterm Infants up to 2 kg.
Normative Left Ventricular M-Mode Echocardiographic Values in Preterm Infants up to 2 kg.
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DOI:
10.1016/j.echo.2017.04.010
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发表时间:
2017-08
期刊:
影响因子:
--
通讯作者:
Johnson MC
中科院分区:
文献类型:
--
作者:
Choudhry S;Salter A;Cunningham TW;Levy PT;Nguyen HH;Wallendorf M;Singh GK;Johnson MC
There is a paucity of normative echocardiographic data in preterm infants. The objectives of this study were: (1) derive left ventricular (LV) M-mode reference values, and (2) compare the performance of alternative methods of indexing LV dimensions and mass (LVM) in preterm infants. We propose that indexing LV measures to weight in preterm infants is a practical approach given the variability associated with tape-measure length measurement in infants. In this retrospective study LV M-mode echocardiographic measurements of end diastolic interventricular septal thickness (IVSd), end diastolic LV posterior wall thickness (LVPWd), LV end diastolic and systolic dimensions (LVEDD, LVESD), LVM, and relative wall thickness (RWT) were remeasured in 503 hospitalized preterm infants ≤ 2 Kg (372 from a retrospective sample and 131 prospectively enrolled). Measures for all variables did not differ between retrospective and prospective samples so results were pooled. LV dimensions and LVM indexed for weight, length, and body surface area (BSA) sex-specific centile curves and corresponding Z scores were generated using Cole’s lambda-mu-sigma method. Threshold limits (10th, and 80th percentile; P10, P80) were used to generate RWT normative range. Sex-specific centile curves using LVM, IVSd, LVPWd, LVEDD, and LVESD indexed to weight were similar to the curves generated using length and BSA. The mean [P10, P80] normal range for RWT was 0.33 (0.26, 0.38). From this large cohort of preterm infants, we developed LV M-mode dimension and LVM centile curves indexed to weight as a practical method to assess LV morphology in preterm infants.
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