Knight’s move thinking? Mild cognitive impairment in a chess player
Knight’s move thinking? Mild cognitive impairment in a chess player
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国际象棋棋手的棋步思维有轻度认知障碍吗？
DOI：
10.1080/13554790490896875
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发表时间：
2005
期刊：
影响因子：
0.8
通讯作者：
M. Rossor
中科院分区：
文献类型：
--
作者：
H. Archer;J. Schott;J. Barnes;Nick C Fox;J. Holton;T. Révész;L. Cipolotti;M. Rossor
我们报告的情况下，国际象棋选手与上级发病前的认知功能谁提出的认知障碍诊所在国立神经病学和神经外科医院有2年的历史，可能的记忆丧失的症状。最初，MRI扫描外观在正常范围内，他的认知评分在正常范围内;随后，他的认知功能恶化，两年后他符合轻度认知障碍（MCI）的标准。出乎意料的是，他在七个月后死于一种不相关的疾病，并对大脑进行了尸检，发现患有晚期阿尔茨海默病（CERAD明确和NIA-Regan研究所高可能性）。本病例强调了在阿尔茨海默病早期评估具有上级病前功能的患者所遇到的困难，并揭示了系列MRI和神经心理学评估在检测和监测早期神经退行性疾病中的价值。我们要感谢约翰·史蒂文斯博士和伦敦国立神经病学和神经外科医院神经心理学系，感谢他们在准备本文时提供的帮助。JMS是阿尔茨海默病协会（英国）研究员; NCF是医学研究理事会临床科学家，NMR正在接受医学研究理事会计划资助。
We report the case of a chess player with superior premorbid cognitive function who presented to the Cognitive Disorders clinic at the National Hospital for Neurology and Neurosurgery with a 2-year history of symptoms of possible memory loss. Initially the MRI scan appearance was within normal limits and his cognitive scores inside the normal range; subsequently his cognitive function deteriorated and he fulfilled criteria for Mild Cognitive Impairment (MCI) two years later. Unexpectedly he died of an unrelated illness seven months later and post mortem examination of the brain was carried out, revealing advanced Alzheimer’s disease (CERAD definite and NIA-Regan Institute high likelihood). This case highlights the difficulties encountered in assessing patients with superior premorbid function in the early stages of Alzheimer’s disease, and reveals the value of serial MRI and neuropsychological assessment in detecting and monitoring early neurodegenerative disease. We would like to thank Dr John Stevens and the Department of Neuropsychology, The National Hospital for Neurology and Neurosurgery, London, for their help in the preparation of this paper. JMS is an Alzheimer Society (UK) Research Fellow; NCF is a Medical Research Council Clinician Scientist, NMR is in receipt of a Medical Research Council Program Grant.
影响因子：
--
作者：
Elias, MF;Beiser, A;D'Agostino, RB
通讯作者：
D'Agostino, RB
影响因子：
19.7
作者：
Rusinek, H;De Santi, S;de Leon, MJ
通讯作者：
de Leon, MJ