An expanding universe of circadian networks in higher plants.
An expanding universe of circadian networks in higher plants.
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DOI:
10.1016/j.tplants.2010.03.003
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发表时间:
2010-05
影响因子:
20.5
通讯作者:
Kay, Steve A.
中科院分区:
文献类型:
--
作者:
Pruneda-Paz, Jose L.;Kay, Steve A.
Extensive circadian clock networks regulate almost every biological process in plants. Clock-controlled physiological responses are coupled with daily oscillations in environmental conditions resulting in enhanced fitness and growth vigor. Identification of core clock components and their associated molecular interactions has established the basic network architecture of plant clocks, which consists of multiple interlocked feedback loops. A hierarchical structure of transcriptional feedback overlaid with regulated protein turnover sets the pace of the clock and ultimately drives all clock-controlled processes. While originally described as linear entities, increasing evidence suggests that many signaling pathways can act as both inputs and outputs within the overall network. Future studies will determine the molecular mechanisms involved in these complex regulatory loops.
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