Metal patch testing in patients with oral symptoms

Metal patch testing in patients with oral symptoms
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对有口腔症状的患者进行金属斑贴试验

DOI:
10.1111/1346-8138.15606
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发表时间:
2020
期刊:
The Journal of Dermatology
影响因子:
--
通讯作者:
Katoh Norito
Katoh Norito
中科院分区:
--
文献类型:
--
作者:
Maeno Misato;Tamagawa‐Mineoka Risa;Arakawa Yukiyasu;Masuda Koji;Adachi Tetsuya;Katoh Norito

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最近,金属过敏患者的数量有所增加,而贴片试验对于调查这类患者很有用。然而,在口腔金属过敏患者中,修复体去除的效果存在争议。本研究旨在探讨口腔症状与金属过敏的关系。我们对60例有口腔症状的患者进行了回顾性分析。最常见的口腔症状是口腔感觉异常。38%的患者表现出对一种或多种金属的阳性过敏反应。镍是最常产生阳性反应的金属过敏原。在移除修复体的7例患者中,分别有1例和2例患者实现了完全缓解和部分缓解。有趣的是,33% (n= 1)的阳性斑贴试验组和50% (n= 2)的非阳性斑贴试验组的金属合金去除是有效的。我们的研究结果表明,仅基于贴片试验来预测修复体移除改善口腔金属过敏的效果是困难的。
The number of patients with metal allergies has increased recently, and patch testing is useful for investigating such patients. However, the efficacy of restoration removal in patients with oral metal allergies is disputed. This study aimed to investigate the relationships between oral symptoms and metal allergies. We conducted a retrospective analysis of 60 patients with oral symptoms. The most common oral symptom was an abnormal oral sensation. Thirty‐eight percent of the patients exhibited positive allergic reactions to one or more metal. Nickel was the metal allergen that produced positive reactions most frequently. Of the seven patients whose restorations were removed, complete and partial remission were achieved in one and two patients, respectively. Interestingly, metal alloy removal was effective in 33% (n= 1) of the positive patch test group and 50% (n= 2) of the non‐positive patch test group. Our results demonstrated the difficulty of predicting the efficacy of restoration removal at ameliorating oral metal allergies based on patch testing alone.
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