The 2013 Nucleic Acids Research Database Issue and the online molecular biology database collection.

The 2013 Nucleic Acids Research Database Issue and the online molecular biology database collection.
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DOI:
10.1093/nar/gks1297
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发表时间:
2013-01
影响因子:
14.9
通讯作者:
Galperin MY
Galperin MY
中科院分区:
生物学2区
文献类型:
--
作者:
Fernández-Suárez XM;Galperin MY

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第20期《核酸研究数据库》包括176篇文章,其中一半描述了新的在线分子生物学数据库,另一半提供了以前发表在NAR和其他期刊上的数据库的更新。今年的重点包括两个DNA重复元件数据库;几个转录因子和转录因子结合位点数据库;蛋白质结构和蛋白质相互作用的各个方面的数据库;元基因组和rRNA序列分析数据库;以及四个专门用于大肠杆菌的数据库。利用基因组数据改善人类健康的日益重视反映在基因组结构变异数据库(NCBI的DBVar和EBI的DGVa)、NIH基因测试登记和其他几个数据库的发展中,这些数据库集中在人类疾病的遗传基础、潜在的药物、它们的靶点和蛋白质-配体结合的机制。两个新的数据库提供了猴子的基因组和RNAseq数据,为比较基因组学目的提供了丰富的人类近亲数据。可在http://www.oxfordjournals.org/nar/database/a/,获得的NAR在线分子生物学数据库已更新,目前列出了1,512个在线数据库。该期数据库的全部内容可在核酸研究网站(http://nar.oxfordjournals.org/).)免费在线查阅
The 20th annual Database Issue of Nucleic Acids Research includes 176 articles, half of which describe new online molecular biology databases and the other half provide updates on the databases previously featured in NAR and other journals. This year’s highlights include two databases of DNA repeat elements; several databases of transcriptional factors and transcriptional factor-binding sites; databases on various aspects of protein structure and protein–protein interactions; databases for metagenomic and rRNA sequence analysis; and four databases specifically dedicated to Escherichia coli. The increased emphasis on using the genome data to improve human health is reflected in the development of the databases of genomic structural variation (NCBI’s dbVar and EBI’s DGVa), the NIH Genetic Testing Registry and several other databases centered on the genetic basis of human disease, potential drugs, their targets and the mechanisms of protein–ligand binding. Two new databases present genomic and RNAseq data for monkeys, providing wealth of data on our closest relatives for comparative genomics purposes. The NAR online Molecular Biology Database Collection, available at http://www.oxfordjournals.org/nar/database/a/, has been updated and currently lists 1512 online databases. The full content of the Database Issue is freely available online on the Nucleic Acids Research website (http://nar.oxfordjournals.org/).
DOI: 10.1093/nar/gks1189
发表时间: 2013-01
影响因子: 14.9
作者:
NCBI Resource Coordinators
通讯作者: NCBI Resource Coordinators
DOI: 10.1159/000084979
发表时间: 2005-01-01
影响因子: 1.7
作者:
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通讯作者: Walichiewicz, J
DOI: 10.1093/nar/gkr1196
发表时间: 2012-01
影响因子: 14.9
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发表时间: 2013-01
影响因子: 14.9
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通讯作者: Teufel A
DOI: 10.1093/nar/gks1236
发表时间: 2013-01
影响因子: 14.9
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通讯作者: Searle SM