Executive functioning in children and adolescents with Major Depressive Disorder.

Executive functioning in children and adolescents with Major Depressive Disorder.
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DOI:
10.1080/09297040802577311
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发表时间:
2009-01
期刊:
Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence
影响因子:
--
通讯作者:
Carmody T
Carmody T
中科院分区:
其他
文献类型:
--
作者:
Favre T;Hughes C;Emslie G;Stavinoha P;Kennard B;Carmody T

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本研究调查了39名患有严重抑郁障碍(MDD)的儿童和青少年和24名8至17岁的健康对照受试者的神经认知功能,重点是执行功能(EF)。采用韦氏儿童智力量表第三版,以及威斯康星卡片分类任务、连线测验、受控口语单词联想测验和Stroop颜色单词测验等多种执行功能测量工具。抑郁症儿童和青少年组的神经认知特征大体上是完整的,因为大多数智力和EF测试的分数都在平均范围内,与对照组没有区别。与正常对照组相比,精神障碍组的心理加工速度降低,27%的抑郁组在连线测试中的成绩低于平均水平。这项研究为比较门诊早发性MDD患者EF的未来文献提供了一个很好的基础。
The present investigation examined neurocognitive functioning, focusing on executive functioning (EF), in 39 children and adolescents with Major Depressive Disorder (MDD) and 24 healthy control subjects all ages 8 to 17 years. The Wechsler Intelligence Scale for Children-Third Edition along with several measures of executive functioning including the Wisconsin Card Sorting Task, Trail Making Test, Controlled Oral Word Association Test, and the Stroop Color Word Test were administered. The neurocognitive profiles for the group of depressed children and adolescents were grossly intact as most scores on intellectual and EF measures fell within the average range and did not differ from the comparison group. Mental processing speed was decreased in the MDD versus normal control group and 27% of the depressed group performed below average on the Trail Making Test. This investigation provided a good base from which to compare future literature on EF in outpatients with early-onset MDD.
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