The Escalating Magnitude of COVID-19 Infections among the Northeastern Ethiopia Region: A Community-Based Cross-Sectional Study.

The Escalating Magnitude of COVID-19 Infections among the Northeastern Ethiopia Region: A Community-Based Cross-Sectional Study.
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DOI:
10.1155/2021/5549893
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发表时间:
2021
影响因子:
3.4
通讯作者:
Gebretsadik D
Gebretsadik D
中科院分区:
其他
文献类型:
--
作者:
Geto Z;Gebremichael S;Belete MA;Gedefie A;Molla G;Tesfaye M;Demsiss W;Gebretsadik D

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新型冠状病毒病(COVID-19)具有致命性和极具传染性,全球流行率迅速上升。世界卫生组织宣布此次疫情为全球大流行;据报道,它已经蔓延到世界上几乎每一个国家。然而,在发达国家和发展中国家之间,以及在同一国家的不同区域内,流行程度各不相同。显而易见的是,从社区调查中估计COVID-19感染的规模对于公共卫生政策制定者做出应对疫情、优化措施和设计缓解计划的决策至关重要。2020年7月1日至8月31日,在埃塞俄比亚东北部地区开展了一项基于社区的横断面研究。采用简单随机抽样技术,从社区调查、确诊病例的接触痕迹和感染疑似病例中选择研究参与者。口咽标本提取病毒核酸后,采用实时荧光聚合酶链反应(RT-PCR)试剂盒检测新型冠状病毒。本研究共纳入8752名研究参与者。男性占63.6%,女性占36.4%。在8752名研究参与者中,发现291人(3.3%)感染了该病毒。第一例实验室确诊病例出现在研究期第四周,即2020年7月24日至7月31日,最后两周出现流行高峰。COVID-19感染在男性和36-52岁年龄组中更为普遍。与其他形式的社区调查相比,通过接触追踪测试的参与者感染COVID-19的可能性为1.65倍(AOR = 1.65, 95% CI = 1.09-2.51, P=0.018)。东北地区新冠肺炎感染趋势呈增量趋势,检测能力的提高对早期发现感染,为预防、治疗和控制国际大流行发挥更大作用。
The novel coronavirus disease (COVID-19) is lethal and extremely contagious, with a rapidly rising global prevalence. The World Health Organization has declared the outbreak a global pandemic; it is reported to have spread to nearly every country in the world. However, the prevalence varies across developed and developing countries, as well as within different regions of the same country. It is not hidden that estimating the magnitude of COVID-19 infection from the community surveys is critical for public health policymakers to make decisions to deal with the outbreak, optimize measures, and design mitigation plans. A community-based cross-sectional study was conducted from 01 July to 31 August 2020 in the northeastern Ethiopia region. A simple random sampling technique was used to select study participants from the community survey, contact traces from confirmed cases, and infection suspects. After extraction of viral nucleic acid from oropharyngeal specimen, the real-time fluorescent polymerase chain reaction (RT-PCR) kit was used for detecting novel coronavirus. A total of 8752 study participants were included in this study. About 63.6% were males and 36.4% were females. Out of the total 8752 study participants, 291 (3.3%) were found to be infected with the virus. The first laboratory-confirmed cases of COVID-19 were detected in the fourth week of the study period, that is, from July 24 to July 31, 2020, and the peak prevalence was observed in the last two weeks. The COVID-19 infection was more prevalent among males and in the age group of 36–52 years. Participants tested via contact trace had 1.65 times (AOR = 1.65, 95% CI = 1.09–2.51, P=0.018) the likelihood of COVID-19 infection in comparison to the other forms of community surveys. The trend in the prevalence of COVID-19 infection in the northeastern region has shown increment, and increasing testing capacity has a greater benefit in identifying early infection for the prevention, treatment, and control of the international pandemic.
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