Mental health consequences of urban air pollution: prospective population-based longitudinal survey.
Mental health consequences of urban air pollution: prospective population-based longitudinal survey.
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DOI：
10.1007/s00127-020-01966-x
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发表时间：
2021-09
影响因子：
4.4
通讯作者：
Mudway IS
中科院分区：
文献类型：
--
作者：
Bakolis I;Hammoud R;Stewart R;Beevers S;Dajnak D;MacCrimmon S;Broadbent M;Pritchard M;Shiode N;Fecht D;Gulliver J;Hotopf M;Hatch SL;Mudway IS
世界卫生组织（WHO）最近将空气污染列为过早死亡的主要环境原因。然而，由于证据有限，世卫组织的报告没有说明与空气质量有关的精神健康不良的重大潜在健康和社会成本。我们的目的是检验长期暴露于空气污染与心理健康状况不佳有关的假设。从2008年到2013年，对居住在南东伦敦1075户家庭的1698名成年人进行了一项前瞻性的基于人口的纵向心理健康调查。高分辨率的二氧化氮（NO2）和氧化物（NOx），臭氧（O3），空气动力学直径< 10 μm（PM10）和< 2.5 μm（PM2.5）的颗粒物的季度平均空气污染浓度与研究参与者的家庭住址有关。在调整大量混杂因素（包括个人的社会经济地位和暴露于道路交通噪声）后，使用多水平广义线性模型分析与心理健康的关联。我们发现了PM2.5、NOx和NO2四分位数范围增加的强有力证据，仅与PM10相关的常见精神障碍的几率增加18-39%，不良身体症状的几率增加19-30%，精神病经历的几率增加33%。这些纵向关联在NO2和NOx的非移动者的子集中更明显。研究结果表明，与交通有关的空气污染对心理健康有不利影响。虽然因果关系无法证明，但这项工作表明，通过改善空气质量，可以避免精神障碍的大量发病率。本文的在线版本（10.1007/s 00127 -020-01966-x）包含补充材料，可供授权用户使用。
The World Health Organisation (WHO) recently ranked air pollution as the major environmental cause of premature death. However, the significant potential health and societal costs of poor mental health in relation to air quality are not represented in the WHO report due to limited evidence. We aimed to test the hypothesis that long-term exposure to air pollution is associated with poor mental health. A prospective longitudinal population-based mental health survey was conducted of 1698 adults living in 1075 households in South East London, from 2008 to 2013. High-resolution quarterly average air pollution concentrations of nitrogen dioxide (NO2) and oxides (NOx), ozone (O3), particulate matter with an aerodynamic diameter < 10 μm (PM10) and < 2.5 μm (PM2.5) were linked to the home addresses of the study participants. Associations with mental health were analysed with the use of multilevel generalised linear models, after adjusting for large number of confounders, including the individuals’ socioeconomic position and exposure to road-traffic noise. We found robust evidence for interquartile range increases in PM2.5, NOx and NO2 to be associated with 18–39% increased odds of common mental disorders, 19–30% increased odds of poor physical symptoms and 33% of psychotic experiences only for PM10. These longitudinal associations were more pronounced in the subset of non-movers for NO2 and NOx. The findings suggest that traffic-related air pollution is adversely affecting mental health. Whilst causation cannot be proved, this work suggests substantial morbidity from mental disorders could be avoided with improved air quality. The online version of this article (10.1007/s00127-020-01966-x) contains supplementary material, which is available to authorized users.
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影响因子：
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作者：
de Prado Bert P;Mercader EMH;Pujol J;Sunyer J;Mortamais M
通讯作者：
Mortamais M
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