Loss of muscle mass in the immediate post-operative period is associated with inadequate dietary protein and energy intake.
Loss of muscle mass in the immediate post-operative period is associated with inadequate dietary protein and energy intake.
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DOI：
10.1038/s41430-023-01264-0
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发表时间：
2023-04
影响因子：
4.7
通讯作者：
中科院分区：
文献类型：
--
作者：
尽管实施了“术后增强恢复”（ERAS）方案，但腹部大手术仍与术后肌肉质量和功能的显著和有害损失相关。尽管ERAS方案提倡早期活动和饮食摄入，但术后即刻的饮食组成特征不佳，尽管这一时期肌肉损失最大。在此，我们发现15例患者（66 ± 6岁，12：3男：女）的m丢失约10%。在开放性结直肠切除术后5天，股外侧肌肌肉质量，平均能量摄入量仅为ESPEN推荐的最低25 kcal/kg/d的约25%，每日膳食蛋白质摄入量仅为ESPEN推荐指南1.5 g/kg/d的约12%。鉴于营养对肌肉质量维持的已知重要性，在术后即刻需要创新的饮食干预，考虑到特定患者的饮食偏好以最大限度地提高依从性（例如，软质食物）。
Despite the implementation of ‘Enhanced Recovery After Surgery’ (ERAS) protocols, major abdominal surgery is still associated with significant and detrimental losses of muscle mass and function in the post-operative period. Although ERAS protocols advocate both early mobility and dietary intake, dietary composition in the immediate post-operative period is poorly characterised, despite muscle losses being greatest in this period. Herein, we show in 15 patients (66 ± 6 y, 12:3 M:F) who lost ~10% m. vastus lateralis muscle mass in the 5 days after open colorectal resective surgery, mean energy intake was only ~25% of the minimum ESPEN recommendation of 25 kcal/kg/d and daily dietary protein intake was only ~12% of the ESPEN recommended guidelines of 1.5 g/kg/d. Given the known importance of nutrition for muscle mass maintenance, innovative dietary interventions are needed in the immediate post-operative period, accounting for specific patient dietary preference to maximise compliance (e.g., soft-textured foods).
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影响因子：
6.7
作者：
通讯作者：
--
影响因子：
6.3
作者：
Weimann, Arved;Braga, Marco;Singer, Pierre
通讯作者：
Singer, Pierre
影响因子：
7.4
作者：
Aoyama, Toru;Kawabe, Taiichi;Yoshikawa, Takaki
通讯作者：
Yoshikawa, Takaki
影响因子：
4.2
作者：
van Wijk L;van Duinhoven S;Liem MSL;Bouman DE;Viddeleer AR;Klaase JM
通讯作者：
Klaase JM
影响因子：
4.2
作者：
Rosenberg, IH
通讯作者：
Rosenberg, IH