A prospective multicentre study in Sweden and Norway of mental distress and psychiatric morbidity in head and neck cancer patients.
A prospective multicentre study in Sweden and Norway of mental distress and psychiatric morbidity in head and neck cancer patients.
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在瑞典和挪威进行的一项前瞻性多中心研究，对头颈癌患者的精神困扰和精神病发病率进行。
DOI：
10.1038/sj.bjc.6690420
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发表时间：
1999-05
影响因子：
8.8
通讯作者：
Westin, T
中科院分区：
文献类型：
--
作者：
Hammerlid, E;Ahlner-Elmqvist, M;Bjordal, K;Biörklund, A;Evensen, J;Boysen, M;Jannert, M;Kaasa, S;Sullivan, M;Westin, T
瑞典/挪威的一项头颈癌研究旨在前瞻性地评估新诊断的头颈癌患者的不同样本中的精神痛苦水平和精神发病率。共纳入357名患者。平均年龄为63岁，其中72%为男性。患者在1年内被要求6次回答HAD量表(医院焦虑和抑郁量表)。焦虑或抑郁障碍的可能或可能病例的数量根据标准化的截止值计算。在研究的一年中，大约三分之一的患者在每个测量点上都被评为可能或可能患有重大情绪障碍的患者。在每个时间点都有新的焦虑或抑郁病例。在确诊时焦虑程度最高，而在治疗期间抑郁最常见。女性在确诊时比男性更焦虑，65岁以下的患者得分高于65岁以上的患者。表现状态较差和疾病较严重的患者报告的精神痛苦水平更高，而且更经常被评为可能或可能的精神障碍病例。我们的心理测量学分析支持HAD量表的二维结构和稳定性。HAD量表似乎是获得有关头颈部癌症人群中情绪障碍概率的有效信息的首选方法。这项研究中发现的精神疾病发病率强调了改进诊断和治疗的重要性。©1999癌症研究活动
A Swedish/Norwegian head and neck cancer study was designed to assess prospectively the levels of mental distress and psychiatric morbidity in a heterogeneous sample of newly diagnosed head and neck cancer patients. A total of 357 patients were included. The mean age was 63 years, and 72% were males. The patients were asked to answer the HAD scale (the Hospital Anxiety and Depression scale) six times during 1 year. The number of possible or probable cases of anxiety or depression disorder was calculated according to standardized cut-offs. Approximately one-third of the patients scored as a possible or probable case of a major mood disorder at each measurement point during the study year. There were new cases of anxiety or depression at each time point. The anxiety level was highest at diagnosis, while depression was most common during treatment. Females were more anxious than males at diagnosis, and patients under 65 years of age scored higher than those over 65. Patients with lower performance status and more advanced disease reported higher levels of mental distress and more often scored as a probable or possible cases of psychiatric disorder. Our psychometric analyses supported the two-dimensional structure and stability of the HAD scale. The HAD scale seems to be the method of choice for getting valid information about the probability of mood disorder in head and neck cancer populations. The prevalence of psychiatric morbidity found in this study emphasizes the importance of improved diagnosis and treatment. © 1999 Cancer Research Campaign
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影响因子：
7
作者：
CARROLL, BT;KATHOL, RG;CLAMON, GH
通讯作者：
CLAMON, GH
影响因子：
5.4
作者：
MAGUIRE, P
通讯作者：
MAGUIRE, P
影响因子：
4.8
作者：
Hammerlid, E;Mercke, C;Westin, T
通讯作者：
Westin, T
影响因子：
3.4
作者：
Hammerlid, E;Bjordal, K;Westin, T
通讯作者：
Westin, T
影响因子：
10.5
作者：
DAVIES, ADM;DAVIES, C;DELPO, MC
通讯作者：
DELPO, MC