An introduction to diffusion tensor image analysis.

An introduction to diffusion tensor image analysis.
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DOI:
10.1016/j.nec.2010.12.004
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发表时间:
2011-04
影响因子:
2.6
通讯作者:
Westin, Carl-Fredrik
Westin, Carl-Fredrik
中科院分区:
医学3区
文献类型:
--
作者:
O'Donnell, Lauren J.;Westin, Carl-Fredrik

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扩散张量磁共振成像(DTI)是一种相对较新的技术,流行用于成像大脑的白色物质。本综述的目的是对DTI进行基本和广泛的概述,以便读者可以对此类数据进行直观的理解,并了解其优点和缺点。为了完整起见,我们试图包括方程,但它们对于理解本文并不是必需的。在可能的情况下,将提供更深入的技术文章或书籍的指针,以供进一步阅读。我们特别推荐新的弥散MRI教科书[1]、关于纤维束和肿瘤的介绍性论文[2]、白色物质图谱书[3]以及DTI分析中潜在陷阱的回顾[4]。在本文的其余部分,我们将解决有关DTI的基本问题(什么,为什么,以及如何DTI),然后讨论DTI的解释问题,最后概述更先进的扩散成像方法和未来的发展方向。
Diffusion tensor magnetic resonance imaging (DTI) is a relatively new technology that is popular for imaging the white matter of the brain. The goal of this review is to give a basic and broad overview of DTI such that the reader may develop an intuitive understanding of this type of data, and an awareness of its strengths and weaknesses. We have tried to include equations for completeness but they are not necessary for understanding the paper. Wherever possible, pointers will be provided to more in-depth technical articles or books for further reading. We especially recommend the new diffusion MRI textbook [1], the introductory paper on fiber tracts and tumors [2], the white matter atlas book [3], and the review of potential pitfalls in DTI analysis [4]. In the rest of this article we will address basic questions about DTI (the what, why, and how of DTI), followed by a discussion of issues in interpretation of DTI, and finally an overview of more advanced diffusion imaging methods and future directions.
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