CodonO: codon usage bias analysis within and across genomes.

CodonO: codon usage bias analysis within and across genomes.
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DOI:
10.1093/nar/gkm392
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发表时间:
2007-07
影响因子:
14.9
通讯作者:
Wan XF
Wan XF
中科院分区:
生物学2区
文献类型:
--
作者:
Angellotti MC;Bhuiyan SB;Chen G;Wan XF

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同义密码子使用偏差与多种生物学因素有关,如基因表达水平、基因长度、基因翻译起始信号、蛋白质氨基酸组成、蛋白质结构、tRNA丰度、突变频率和模式、GC组成等。密码子使用偏差的量化有助于理解生物体的进化。密码子使用偏倚管道是基因组内和基因组间密码子使用偏倚分析的必要条件。在这里,我们提出了一个密码子网络服务器服务,作为一个用户友好的工具,密码子使用偏差分析跨和基因组内的实时。web服务器可在http//www.sysbiology.org/CodonO上获得。联系:wanhenry@yahoo.com。
Synonymous codon usage biases are associated with various biological factors, such as gene expression level, gene length, gene translation initiation signal, protein amino acid composition, protein structure, tRNA abundance, mutation frequency and patterns, and GC compositions. Quantification of codon usage bias helps understand evolution of living organisms. A codon usage bias pipeline is demanding for codon usage bias analyses within and across genomes. Here we present a CodonO webserver service as a user-friendly tool for codon usage bias analyses across and within genomes in real time. The webserver is available at http//www.sysbiology.org/CodonO. Contact: wanhenry@yahoo.com.
DOI: 10.1093/nar/12.1part2.539
发表时间: 1984-01-01
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