Health-related quality of life (HRQOL) decreases independently of chronic conditions and geriatric syndromes in older adults with diabetes: the Fujiwara-kyo Study.
Health-related quality of life (HRQOL) decreases independently of chronic conditions and geriatric syndromes in older adults with diabetes: the Fujiwara-kyo Study.
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DOI：
10.2188/jea.je20130131
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发表时间：
2014
影响因子：
4.7
通讯作者：
Kurumatani N
中科院分区：
文献类型：
--
作者：
Nezu S;Okamoto N;Morikawa M;Saeki K;Obayashi K;Tomioka K;Komatsu M;Iwamoto J;Kurumatani N
很少有研究调查糖尿病与老年人健康相关生活质量（HRQOL）受损之间的关系，独立于慢性疾病和老年综合征。我们对3946名65岁以上的老年人进行了自填式问卷调查和结构化访谈，以获得糖尿病、慢性病和老年综合征的病史。进行血液检查以测量糖化血红蛋白（HbA 1c）和血糖水平。使用医学结局研究36项简表一般健康调查（SF-36）评估HRQOL，并使用多元logistic回归分析计算低HRQOL的校正比值比和95% CI。共有3521名参与者没有接受过糖尿病的医生诊断。其中，2345名HbA 1c低于5.7%的参与者被定义为参考组。与参照组相比，1029名HbA 1c至少为5.7%但小于6.5%的受试者在调整慢性疾病、老年综合征和其他潜在混杂因素后，SF-36身体、精神和角色成分总结的QOL没有显著降低。然而，572例经医生诊断为糖尿病和/或HbA 1c ≥ 6.5%的患者的低身体成分汇总的校正比值比（1.48; 95% CI，1.18-1.84）显著更高。在425名接受糖尿病治疗的参与者中，在3个组成部分的任何一个总结中，均未发现与血糖控制、治疗方案或糖尿病持续时间相关的显著差异。日本老年糖尿病患者的身体生活质量下降，独立于慢性疾病和老年综合征。
Very few studies have investigated the association between diabetes and impaired health-related quality of life (HRQOL) in older adults, independent of chronic conditions and geriatric syndromes. We conducted a self-administered questionnaire survey and structured interviews with 3946 people aged 65 years or older to obtain medical histories of diabetes, chronic conditions, and geriatric syndromes. Blood tests were performed to measure glycated hemoglobin (HbA1c) and plasma glucose levels. HRQOL was evaluated using the Medical Outcomes Study 36-Item Short-Form General Health Survey (SF-36), and multiple logistic regression analysis was used to calculate adjusted odds ratios and 95% CIs for low HRQOL. A total of 3521 participants had not received a physician diagnosis of diabetes. Of these, 2345 participants with an HbA1c less than 5.7% were defined as the referent group. As compared with the referent group, 1029 participants with an HbA1c of at least 5.7% but less than 6.5% showed no significant decrease in QOL on the SF-36 physical, mental, and role component summaries, after adjustment for chronic conditions, geriatric syndromes, and other potential confounders. However, 572 patients who had received a physician diagnosis of diabetes and/or had an HbA1c of 6.5% or higher had a significantly higher adjusted odds ratio (1.48; 95% CI, 1.18–1.84) for the low physical component summary. No significant differences in relation to glycemic control, treatment regimen, or diabetes duration were found in any of the 3 component summaries among the 425 participants who were undergoing diabetes treatment. Older Japanese adults with diabetes had decreased physical QOL, independent of chronic conditions and geriatric syndromes.
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影响因子：
7.2
作者：
Fukuhara, S;Bito, S;Kurokawa, K
通讯作者：
Kurokawa, K
影响因子：
16.2
作者：
通讯作者：
--
影响因子：
3.6
作者：
Graham, James E.;Stoebner-May, Diane G.;Ottenbacher, Kenneth J.
通讯作者：
Ottenbacher, Kenneth J.
影响因子：
16.2
作者：
Park, Seok Won;Goodpaster, Bret H.;Newman, Anne B.
通讯作者：
Newman, Anne B.
DOI：
10.1111/j.1532-5415.2006.00681.x
发表时间：
2006-04-01
影响因子：
6.3
作者：
Dorr, DA;Jones, SS;Clayton, PD
通讯作者：
Clayton, PD