Enriching for orthologs increases support for Xenacoelomorpha and Ambulacraria sister relationship
Enriching for orthologs increases support for Xenacoelomorpha and Ambulacraria sister relationship
复制标题
丰富直向同源物增加了对 Xenacoelomorpha 和 Ambulacaria 姐妹关系的支持
DOI:
10.1101/2021.12.13.472462
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发表时间:
2021
期刊:
影响因子:
--
通讯作者:
Mulhair P
中科院分区:
文献类型:
--
作者:
Mulhair P
Conflicting studies place a group of bilaterian invertebrates containing xenoturbellids and acoelomorphs, the Xenacoelomorpha, as either the primary emerging bilaterian phylum1,2,3,4,5,6or within Deuterostomia, sister to Ambulacraria.7,8,9,10,11Although their placement as sister to the rest of Bilateria supports relatively simple morphology in the ancestral bilaterian, their alternative placement within Deuterostomia suggests a morphologically complex ancestral bilaterian along with extensive loss of major phenotypic traits in the Xenacoelomorpha. Recent studies have questioned whether Deuterostomia should be considered monophyletic at all.10,12,13Hidden paralogy and poor phylogenetic signal present a major challenge for reconstructing species phylogenies.14,15,16,17,18Here, we assess whether these issues have contributed to the conflict over the placement of Xenacoelomorpha. We reanalyzed published datasets, enriching for orthogroups whose gene trees support well-resolved clans elsewhere in the animal tree.16We find that most genes in previously published datasets violate incontestable clans, suggesting that hidden paralogy and low phylogenetic signal affect the ability to reconstruct branching patterns at deep nodes in the animal tree. We demonstrate that removing orthogroups that cannot recapitulate incontestable relationships alters the final topology that is inferred, while simultaneously improving the fit of the model to the data. We discover increased, but ultimately not conclusive, support for the existence of Xenambulacraria in our set of filtered orthogroups. At a time when we are progressing toward sequencing all life on the planet, we argue that long-standing contentious issues in the tree of life will be resolved using smaller amounts of better quality data that can be modeled adequately.19
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影响因子:
9.2
作者:
Feuda, Roberto;Dohrmann, Martin;Pisani, Davide
通讯作者:
Pisani, Davide
DOI:
10.1101/2020.07.01.182915
发表时间:
2020
期刊:
--
影响因子:
--
作者:
Kapli P
通讯作者:
Kapli P
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6.5
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Brown, Jeremy M.;Thomson, Robert C.
通讯作者:
Thomson, Robert C.
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64.8
作者:
Philippe, Herve;Brinkmann, Henner;Copley, Richard R.;Moroz, Leonid L.;Nakano, Hiroaki;Poustka, Albert J.;Wallberg, Andreas;Peterson, Kevin J.;Telford, Maximilian J.
通讯作者:
Telford, Maximilian J.
影响因子:
1.6
作者:
Iñaki Ruiz;Jordi Paps
通讯作者:
Jordi Paps