Postnatal development of rat nucleus tractus solitarius neurons: morphological and electrophysiological evidence
Postnatal development of rat nucleus tractus solitarius neurons: morphological and electrophysiological evidence
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大鼠孤束核神经元的出生后发育：形态学和电生理学证据
DOI：
10.1016/s0306-4522(99)00109-8
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发表时间：
1999
期刊：
影响因子：
3.3
通讯作者：
F. Tell
中科院分区：
文献类型：
--
作者：
A. Vincent;F. Tell
应用Golgi-Cox技术和全细胞记录技术对大鼠孤束核尾侧核神经元的生后发育进行了研究。根据体细胞和树突状细胞的形态，定义了两类细胞。伸长的神经元有两个粗的初级树突起源于索马的长轴。初级树突，向远端逐渐变细，产生一到四个次级树突。多极神经元有锥体细胞体。从每个顶点的细胞体是一个长的初级树突，这引起了一个变量的二级树突。从出生到成年，这两个阶层的相对比例相当恒定。在出生后的头两周，树突的长度和影响面积增加，但神经元的几何形状没有改变，在任何一类。树突状附属物在生后5天出现，在生后P12天达到高峰，然后在成年神经元中几乎消失。结合细胞内注射神经生物素和全细胞记录表明，尾侧孤束核神经元的形态学改变与被动特性和尖峰特性的变化平行发生。然而，放电的点火模式是不相关的形态。这些结果的生理意义进行了讨论。
Postnatal development of neurons in the caudal nucleus tractus solitarii of rats was studied using the Golgi–Cox technique and whole-cell recordings. Two cell classes were defined on the basis of somatic and dendritic morphology. Elongated neurons have two thick primary dendrites originating from the long axis of the soma. The primary dendrites, tapering distally, give rise to one to four secondary dendrites. Multipolar neurons have pyramidal somas. Extending from each apex of the cell body was a long primary dendrite, which gave rise to a variable number of secondary dendrites. The relative proportion of the two classes was rather constant from birth to adulthood. During the first two postnatal weeks, dendritic length and area of influence increase, but neuronal geometry is not altered in either class. Dendritic appendages appear by postnatal day 5, reach a peak at postnatal day P12 and then almost disappear in adult neurons. Combined intracellular injection of neurobiotin and whole-cell recordings indicate that morphological alteration of caudal nucleus tractus solitarius neurons occurs in parallel with changes in passive properties and spike characteristics. However, the firing pattern of discharge is not correlated with morphology. The physiological significance of these results is discussed.
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影响因子：
3.7
作者：
Nemoto TK;Ohara Nemoto Y
通讯作者：
Ohara Nemoto Y
影响因子：
2.5
作者：
KING, CT;HILL, DL
通讯作者：
HILL, DL
新生大鼠动脉化学反射的发展和颈动脉体儿茶酚胺的周转。
DOI：
10.1113/jphysiol.1990.sp018099
发表时间：
1990
期刊：
The Journal of physiology
影响因子：
--
作者：
Hertzberg,T;Hellström,S;Lagercrantz,H;Pequignot,JM
通讯作者：
Pequignot,JM
大鼠胎儿发育过程中迷走神经感觉运动回路的建立。
DOI：
10.1002/neu.480240509
发表时间：
1993
期刊：
Journal of neurobiology
影响因子：
--
作者：
Rinaman,L;Levitt,P
通讯作者：
Levitt,P