Spontaneous Eye Blink Rate During the Working Memory Delay Period Predicts Task Accuracy.
Spontaneous Eye Blink Rate During the Working Memory Delay Period Predicts Task Accuracy.
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DOI：
10.3389/fpsyg.2022.788231
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发表时间：
2022
影响因子：
3.8
通讯作者：
Ellmore TM
中科院分区：
文献类型：
--
作者：
Ortega J;Plaska CR;Gomes BA;Ellmore TM
自发性眨眼频率(SEBR)与注意力和记忆，特别是工作记忆(WM)有关。SEBR还与纹状体多巴胺(DA)活性有关，精神分裂症和帕金森病患者SEBR分别呈上升和下降趋势。过去对SEBR和WM的研究的一个弱点是，在执行用于评估WM的任务之前或之后，使用基线上的眨眼频率来报告相关性。本研究的目的是了解视觉工作记忆任务不同阶段的SEBR波动如何预测任务的准确性。在两个实验中，通过在磁共振成像孔内外收集SEBR的记录，我们观察到SEBR与WM延迟期内的WM任务准确性呈正相关。我们还发现了任务相关的SEBR调制，包括与休息相比，延迟期的SEBR更高，而在要求视觉注意的任务阶段(例如刺激编码)，SEBR更低。这些结果进一步证明SEBR可能是WM任务绩效的一个重要预测因子，其在延迟期的变化表明在WM维护中起作用。讨论了SEBR与DA活性和WM维持的关系。
Spontaneous eye blink rate (sEBR) has been linked to attention and memory, specifically working memory (WM). sEBR is also related to striatal dopamine (DA) activity with schizophrenia and Parkinson’s disease showing increases and decreases, respectively, in sEBR. A weakness of past studies of sEBR and WM is that correlations have been reported using blink rates taken at baseline either before or after performance of the tasks used to assess WM. The goal of the present study was to understand how fluctuations in sEBR during different phases of a visual WM task predict task accuracy. In two experiments, with recordings of sEBR collected inside and outside of a magnetic resonance imaging bore, we observed sEBR to be positively correlated with WM task accuracy during the WM delay period. We also found task-related modulation of sEBR, including higher sEBR during the delay period compared to rest, and lower sEBR during task phases (e.g., stimulus encoding) that place demands on visual attention. These results provide further evidence that sEBR could be an important predictor of WM task performance with the changes during the delay period suggesting a role in WM maintenance. The relationship of sEBR to DA activity and WM maintenance is discussed.
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影响因子：
4.3
作者：
Gramfort A;Luessi M;Larson E;Engemann DA;Strohmeier D;Brodbeck C;Goj R;Jas M;Brooks T;Parkkonen L;Hämäläinen M
通讯作者：
Hämäläinen M
影响因子：
10.6
作者：
Cools, Roshan;D'Esposito, Mark
通讯作者：
D'Esposito, Mark
影响因子：
56.9
作者：
Courtney, SM;Petit, L;Haxby, JV
通讯作者：
Haxby, JV
影响因子：
3.2
作者：
de Frias, Cindy M.;Marklund, Petter;Nyberg, Lars
通讯作者：
Nyberg, Lars
影响因子：
56.9
作者：
FUSTER, JM;ALEXANDER, GE
通讯作者：
ALEXANDER, GE