What boxing tells us about repetitive head trauma and the brain.

What boxing tells us about repetitive head trauma and the brain.
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DOI:
10.1186/alzrt177
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发表时间:
2013
期刊:
Alzheimer's research & therapy
影响因子:
--
通讯作者:
Banks S
Banks S
中科院分区:
其他
文献类型:
--
作者:
Bernick C;Banks S

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拳击和其他格斗运动可以作为人体模型来研究重复性头部创伤对大脑结构和功能的影响。现在被称为慢性创伤性脑病 (CTE) 的最初描述是在 1928 年拳击手身上报道的。在随后的几年中,针对拳击手的研究描述了 CTE 的临床特征、其与战斗暴露程度的关系以及一系列放射学检查结果。该领域因研究设计、缺乏纵向随访以及缺乏商定的 CTE 临床标准等问题而受到阻碍。最近启动的一项针对职业拳击手的前瞻性队列研究——职业拳击手大脑健康研究,试图克服研究拳击手时遇到的一些问题。在这里,我们回顾了该项目第一年的横截面结果。
Boxing and other combat sports may serve as a human model to study the effects of repetitive head trauma on brain structure and function. The initial description of what is now known as chronic traumatic encephalopathy (CTE) was reported in boxers in 1928. In the ensuing years, studies examining boxers have described the clinical features of CTE, its relationship to degree of exposure to fighting, and an array of radiologic findings. The field has been hampered by issues related to study design, lack of longitudinal follow-up, and absence of agreed-upon clinical criteria for CTE. A recently launched prospective cohort study of professional fighters, the Professional Fighters Brain Health Study, attempts to overcome some of the problems in studying fighters. Here, we review the cross-sectional results from the first year of the project.
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