Exercise and cognition: results from the National Long Term Care Survey.

Exercise and cognition: results from the National Long Term Care Survey.
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DOI:
10.1016/j.jalz.2010.02.004
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发表时间:
2010-11
期刊:
Alzheimer's & dementia : the journal of the Alzheimer's Association
影响因子:
--
通讯作者:
Trojanowski JQ
Trojanowski JQ
中科院分区:
其他
文献类型:
--
作者:
Jedrziewski MK;Ewbank DC;Wang H;Trojanowski JQ

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年龄仍然是阿尔茨海默病和其他痴呆症的一个强有力的风险因素。因此,如果找不到预防性干预措施,美国人口老龄化将导致痴呆症患病率急剧上升。这项研究的目的是检查锻炼和降低认知障碍风险之间的潜在联系。使用国家长期护理调查(NLTCS)数据。在基线(1994)时测量运动参与水平,在基线以及5年和10年随访时测量认知损害状况。进行了线性回归,控制了年龄、性别、教育程度、认知测试的基线分数、糖尿病和高血压。在10年的随访中,不同类型运动的次数与认知障碍的发生呈负相关(p=0.002),持续至少20分钟的运动的次数(p=0.007)也是如此。来自NLTCS数据的研究结果提供了证据,支持锻炼降低痴呆症风险的潜力。
Age remains a robust risk factor for Alzheimer’s disease as well as other dementias. Therefore, the aging of the population in the United States will result in dramatic increases in the prevalence of dementia if preventative interventions are not identified. The aim of this study was to examine potential associations between exercise and lowering the risk of cognitive impairment. National Long Term Care Survey (NLTCS) data were used. Level of exercise participation was measured at baseline (1994) and cognitive impairment status was measured at baseline and 5- and 10-year follow-up. Linear regression was performed, controlling for age, sex, education, baseline score on cognitive test, diabetes and hypertension. At 10-year follow-up, the number of different types of exercises performed was inversely associated with the onset of cognitive impairment (p=0.002) as was the number of exercise sessions lasting at least 20 minutes (p=0.007). Study results from NLTCS data provide evidence supporting the potential for exercise to lower the risk of dementia.
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