Multi-omic approaches for host-microbiome data integration.
Multi-omic approaches for host-microbiome data integration.
复制标题
用于宿主微生物组数据整合的多组学方法。
DOI：
10.1080/19490976.2023.2297860
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发表时间：
2024-01
期刊：
影响因子：
12.2
通讯作者：
中科院分区：
文献类型：
--
作者：
The gut microbiome interacts with the host through complex networks that affect physiology and health outcomes. It is becoming clear that these interactions can be measured across many different omics layers, including the genome, transcriptome, epigenome, metabolome, and proteome, among others. Multi-omic studies of the microbiome can provide insight into the mechanisms underlying host-microbe interactions. As more omics layers are considered, increasingly sophisticated statistical methods are required to integrate them. In this review, we provide an overview of approaches currently used to characterize multi-omic interactions between host and microbiome data. While a large number of studies have generated a deeper understanding of host-microbiome interactions, there is still a need for standardization across approaches. Furthermore, microbiome studies would also benefit from the collection and curation of large, publicly available multi-omics datasets.
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影响因子：
4.7
作者：
Gomez-Llorente MA;Martínez-Cañavate A;Chueca N;Rico MC;Romero R;Anguita-Ruiz A;Aguilera CM;Gil-Campos M;Mesa MD;Khakimov B;Morillo JA;Gil Á;Camacho J;Gomez-Llorente C
通讯作者：
Gomez-Llorente C
人类微生物组综合项目：在人类健康和疾病期间，微生物组主宿主体剖面的动态分析。
影响因子：
30.3
作者：
Integrative HMP (iHMP) Research Network Consortium
通讯作者：
Integrative HMP (iHMP) Research Network Consortium
HMDB：人类代谢组数据库。
影响因子：
14.9
作者：
Wishart, David S;Tzur, Dan;Knox, Craig;Eisner, Roman;Guo, An Chi;Young, Nelson;Cheng, Dean;Jewell, Kevin;Arndt, David;Sawhney, Summit;Fung, Chris;Nikolai, Lisa;Lewis, Mike;Coutouly, Marie-Aude;Forsythe, Ian;Tang, Peter;Shrivastava, Savita;Jeroncic, Kevin;Stothard, Paul;Amegbey, Godwin;Block, David;Hau, David D;Wagner, James;Miniaci, Jessica;Clements, Melisa;Gebremedhin, Mulu;Guo, Natalie;Zhang, Ying;Duggan, Gavin E;Macinnis, Glen D;Weljie, Alim M;Dowlatabadi, Reza;Bamforth, Fiona;Clive, Derrick;Greiner, Russ;Li, Liang;Marrie, Tom;Sykes, Brian D;Vogel, Hans J;Querengesser, Lori
通讯作者：
Querengesser, Lori
影响因子：
16.6
作者：
Ebrahim, Ali;Brunk, Elizabeth;Tan, Justin;O'Brien, Edward J.;Kim, Donghyuk;Szubin, Richard;Lerman, Joshua A.;Lechner, Anna;Sastry, Anand;Bordbar, Aarash;Feist, Adam M.;Palsson, Bernhard O.
通讯作者：
Palsson, Bernhard O.
影响因子：
6
作者：
Thielemann N;Herz M;Kurzai O;Martin R
通讯作者：
Martin R