Investigation of the limitations of the highly pixilated CdZnTe detector for PET applications.
Investigation of the limitations of the highly pixilated CdZnTe detector for PET applications.
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对宠物应用高度像素化的CDZNTE检测器的局限性的研究。
DOI：
10.1088/0031-9155/57/22/7355
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发表时间：
2012-11-21
影响因子：
3.5
通讯作者：
Tai YC
中科院分区：
文献类型：
--
作者：
Komarov S;Yin Y;Wu H;Wen J;Krawczynski H;Meng LJ;Tai YC
我们正在研究一种基于阳极像素间距为350μm的镉锌碲探测器的高分辨率正电子发射断层扫描插入器集成到传统动物正电子发射断层扫描仪中以提高其图像分辨率的可行性。在本文中，我们使用了一种简化版本的多像素CdZnTe平面探测器，厚度为5 mm，只有9个阳极像素。这种简化的9阳极像素结构使得在没有仍在开发中的完整的专用集成电路读出系统的情况下进行实验成为可能。特别注意了双像素(或电荷共享)探测。实验结果表明：511keV伽马的单像素和双像素光电探测的能量分辨率分别为7%和9%，单像素和双像素探测的时间分辨率分别为30 ns和35 ns(光电相互作用仅为20 ns和25 ns)，x、y面上位置分辨率为350μm，相互作用深度约为0.4 mm。实验测量伴随着蒙特卡罗(MC)模拟，以找出空间电荷分布施加的限制。MC模拟结果表明，对于511keV光电相互作用，该探测器的本征空间分辨率极限为170μm，像素间内插不能恢复超过上述光电相互作用极限的分辨率。然而，使用康普顿散射事件的内插可以获得更高的空间分辨率。在511keV和2 ns半高宽下，所设计的350μm阳极点间距探测器的能量和时间分辨率分别不优于0.6%半高宽。通过了解MC方法的内在局限性，这些MC结果应该被用作了解像素化的镉锌Te探测器由于潜在的检测过程而产生的性能限制的指南。
We are investigating the feasibility of a high resolution positron emission tomography (PET) insert device based on the CdZnTe detector with 350 μm anode pixel pitch to be integrated into a conventional animal PET scanner to improve its image resolution. In this paper, we have used a simplified version of the multi pixel CdZnTe planar detector, 5 mm thick with 9 anode pixels only. This simplified 9 anode pixel structure makes it possible to carry out experiments without a complete application-specific integrated circuits readout system that is still under development. Special attention was paid to the double pixel (or charge sharing) detections. The following characteristics were obtained in experiment: energy resolution full-width-at-half-maximum (FWHM) is 7% for single pixel and 9% for double pixel photoelectric detections of 511 keV gammas; timing resolution (FWHM) from the anode signals is 30 ns for single pixel and 35 ns for double pixel detections (for photoelectric interactions only the corresponding values are 20 and 25 ns); position resolution is 350 μm in x,y-plane and ~0.4 mm in depth-of-interaction. The experimental measurements were accompanied by Monte Carlo (MC) simulations to find a limitation imposed by spatial charge distribution. Results from MC simulations suggest the limitation of the intrinsic spatial resolution of the CdZnTe detector for 511 keV photoelectric interactions is 170 μm. The interpixel interpolation cannot recover the resolution beyond the limit mentioned above for photoelectric interactions. However, it is possible to achieve higher spatial resolution using interpolation for Compton scattered events. Energy and timing resolution of the proposed 350 μm anode pixel pitch detector is no better than 0.6% FWHM at 511 keV, and 2 ns FWHM, respectively. These MC results should be used as a guide to understand the performance limits of the pixelated CdZnTe detector due to the underlying detection processes, with the understanding of the inherent limitations of MC methods.
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用于成像应用的 600 μm 节距像素化 CZT 探测器的电荷共享效应
影响因子：
1.8
作者：
Yin Y;Chen X;Wu H;Komarov S;Garson A 3rd;Li Q;Guo Q;Krawczynski H;Meng LJ;Tai YC
通讯作者：
Tai YC
影响因子：
3.5
作者：
Song TY;Wu H;Komarov S;Siegel SB;Tai YC
通讯作者：
Tai YC
影响因子：
1.8
作者：
Komarov SA;Wu H;Keesing DB;O'Sullivan JA;Tai YC
通讯作者：
Tai YC
DOI：
10.1016/s0168-9002(99)00388-5
发表时间：
1999-08-11
影响因子：
1.4
作者：
Bolotnikov, AE;Cook, WR;Eichelberger, AC
通讯作者：
Eichelberger, AC
影响因子：
3.5
作者：
Qi, Jinyi;Yang, Yongfeng;Cherry, Simon R.
通讯作者：
Cherry, Simon R.