Early experience of pre- and post-contrast 7.0T MRI in brain tumors.

Early experience of pre- and post-contrast 7.0T MRI in brain tumors.
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DOI:
10.3346/jkms.2013.28.9.1362
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发表时间:
2013-09
影响因子:
4.5
通讯作者:
Cho ZH
Cho ZH
中科院分区:
医学4区
文献类型:
--
作者:
Paek SL;Chung YS;Paek SH;Hwang JH;Sohn CH;Choi SH;Son YD;Kim YB;Kim DG;Lee KH;Cho ZH

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我们研究了7.0特斯拉(T)脑磁共振成像(MRI)在脑肿瘤患者中的安全性和临床适用性。本研究纳入了24例轴内或轴外脑肿瘤患者。7.0T磁共振横断面T2* 加权和冠状或矢状位T1加权成像,并与1.5T颅脑磁共振成像进行比较。7.0T脑MRI的T2加权像显示幕上脑肿瘤的微血管和内部内容物的清晰度优于1.5T脑MRI。对于位于鞍旁区域或邻近主要脑血管的区域的脑肿瘤,在7.0T脑MRI中夸大了血流相关伪影。对于邻近颅底的脑肿瘤,在7.0T脑MRI中,鼻窦和颅底交界区的磁敏感伪影阻碍了对脑肿瘤的详细图像和信息的获取。本研究表明,7.0T脑MRI可以提供幕上脑肿瘤的瘤内成分和边缘的详细信息。需要进一步的研究来开发精确的MRI方案,以更好地显示位于颅底、鞍旁和邻近主要脑血管结构的脑肿瘤。
We investigated the safety and clinical applicability of 7.0 Tesla (T) brain magnetic resonance imaging (MRI) in patients with brain tumors. Twenty-four patients with intraaxial or extraaxial brain tumors were enrolled in this study. 7.0T MRIs of T2*-weighted axial and T1-weighted coronal or sagittal images were obtained and compared with 1.5T brain MRIs. The T2*-weighted images from 7.0T brain MRI revealed detailed microvasculature and the internal contents of supratentorial brain tumors better than that of 1.5T brain MRI. For brain tumors located in parasellar areas or areas adjacent to major cerebral vessels, flow-related artifacts were exaggerated in the 7.0T brain MRIs. For brain tumors adjacent to the skull base, susceptibility artifacts in the interfacing areas of the paranasal sinus and skull base hampered the aquisition of detailed images and information on brain tumors in the 7.0T brain MRIs. This study shows that 7.0T brain MRI can provide detailed information on the intratumoral components and margins in supratentorial brain tumors. Further studies are needed to develop refined MRI protocols for better images of brain tumors located in the skull base, parasellar, and adjacent major cerebrovascular structures.
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