Photochemical addition of amino acids and peptides to DNA.
Photochemical addition of amino acids and peptides to DNA.
复制标题
DNA 上氨基酸和肽的光化学加成。
DOI：
10.1111/j.1751-1097.1984.tb03417.x
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发表时间：
1984
影响因子：
3.3
通讯作者：
Hom,K
中科院分区：
文献类型：
--
作者：
Shetlar,MD;Christensen,J;Hom,K
The quantum yields for photochemical addition of twenty of the amino acids commonly occurring in proteins to denatured calf thymus DNA have been determined in deoxygenated phosphate buffer at λ 254 nM and pH 7 using a fluorescamine assay technique. Fifteen were found to be reactive, with cysteine, lysine, phenylalanine, tryptophan and tyrosine being the most reactive. Alanine, aspartic acid, glutamic acid, serine and threonine were unreactive. Analogous quantum yields for a series of eighteen peptides of the form glycyl X (X being one of the commonly occurring amino acids) were also determined, along with the corresponding quantum yields for L‐alanyl‐L‐alanine, L‐alanyl‐L‐tryptophan, L‐seryl‐L‐seryl‐L‐serine, L‐threonyl‐L‐threonyl‐L‐threonine, and L‐cystine‐bis‐glycine. All of the peptides were found to be reactive. The modified amino acids Nε‐methyllysine, Nε, Nε, Nε‐trimethyllysine and Nε‐acetyllysine, all occurring in minor amounts in the histone group of chromosomal proteins, were also found to be reactive as was Nα‐acetyllysine. The quantum yields for photoaddition of a selected group of amino acids and peptides to denatured DNA and native DNA are compared. In some cases higher quantum yields for photoaddition to denatured DNA are observed while in other cases the reverse is true. The effect of oxygen on the quantum yields for photoaddition of selected peptides to DNA was examined. While for most systems studied the amount of reaction in aerated systems was less than in deoxygenated systems, in the case of glycyl‐L‐phenylalanine the reverse was true.
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X 射线处理后昆虫和哺乳动物细胞系的存活率和计划外 DNA 合成的比较。
DOI：
10.1016/0027-5107(78)90114-8
发表时间：
1978
期刊：
Mutation research
影响因子：
--
作者：
T. Koval;W. Myser;R. Hart;W. Hink
通讯作者：
W. Hink
通过重新激活光来减少果蝇中紫外线诱导的表型频率。
影响因子：
56.9
作者：
M. Perlitsh;A. Kelner
通讯作者：
A. Kelner
二聚体切除率、DNA 修复复制率以及人体细胞从紫外线辐射引起的潜在致命损伤中恢复的相关性。
影响因子：
3.4
作者：
B. Konze;J. Levinson;V. Maher;J. Mccormick
通讯作者：
J. Mccormick
紫外线照射的培养鱼细胞 (CAF-MM1) 的存活率和光反应性。
影响因子：
3.4
作者：
Y. Mano;H. Mitani;H. Etoh;N. Egami
通讯作者：
N. Egami
昆虫胚胎中信使 RNA 的光可逆紫外线灭活（Smittia SPEC.、摇蚊科、双翅目）
影响因子：
3.3
作者：
H. Jäckle;K. Kalthoff
通讯作者：
K. Kalthoff