Willingness to participate in future HIV prevention studies among gay and bisexual men in Scotland, UK: a challenge for intervention trials.

Willingness to participate in future HIV prevention studies among gay and bisexual men in Scotland, UK: a challenge for intervention trials.
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DOI:
10.1007/s10461-011-0044-6
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发表时间:
2012-08
期刊:
影响因子:
4.4
通讯作者:
Hart, Graham J.
Hart, Graham J.
中科院分区:
医学2区
文献类型:
--
作者:
McDaid, Lisa M.;Hart, Graham J.

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本文探讨了英国苏格兰同性恋和双性恋男性参与未来艾滋病毒预防研究的意愿。匿名、自填问卷和 Orasure™ 口腔液样本是在商业同性恋场所收集的。 1,320 名男性有资格入选。 78.2%表示愿意参与未来的艾滋病毒预防研究; 64.6% 的人认为 HIV 疫苗,57.4% 的人认为行为改变研究,53.0% 的人认为直肠杀菌剂。在多变量分析中,对于艾滋病毒疫苗研究,年龄较大、少数族裔以及不提供口腔液样本与较低的意愿相关;异性恋取向和不提供口腔液样本用于杀菌剂;高等教育和艾滋病毒治疗更加乐观有助于行为改变。性传播感染测试仍然与更愿意参与杀菌剂研究相关,而频繁使用同性恋场景仍然与更愿意参与行为改变研究相关。过去 12 个月内患有性传播感染与愿意参加所有三种研究类型仍然显着相关。危险性行为和性意愿之间没有关联。尽管大多数男性表示愿意参与未来的研究,但招募有可能受益最多的高风险男性可能更具挑战性。
This article examines willingness to participate in future HIV prevention research among gay and bisexual men in Scotland, UK. Anonymous, self-complete questionnaires and Orasure™ oral fluid samples were collected in commercial gay venues. 1,320 men were eligible for inclusion. 78.2% reported willingness to participate in future HIV prevention research; 64.6% for an HIV vaccine, 57.4% for a behaviour change study, and 53.0% for a rectal microbicide. In multivariate analysis, for HIV vaccine research, greater age, minority ethnicity, and not providing an oral fluid sample were associated with lower willingness; heterosexual orientation and not providing an oral fluid sample were for microbicides; higher education and greater HIV treatment optimism were for behaviour change. STI testing remained associated with being more willing to participate in microbicide research and frequent gay scene use remained associated with being more willing to participate in behaviour change research. Having an STI in the past 12 months remained significantly associated with being willing to participate in all three study types. There were no associations between sexual risk behaviour and willingness. Although most men expressed willingness to participate in future research, recruitment of high-risk men, who have the potential to benefit most, is likely to be more challenging.
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