The Gene Ontology project in 2008.

The Gene Ontology project in 2008.
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DOI:
10.1093/nar/gkm883
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发表时间:
2008-01
影响因子:
14.9
通讯作者:
Gene Ontology Consortium
Gene Ontology Consortium
中科院分区:
生物学2区
文献类型:
--
作者:
Gene Ontology Consortium

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基因本体论(GO)项目(http://www.geneontology.org/))提供了一组结构化的、受控的词汇表,供社区在注释基因、基因产品和序列时使用(另见http://www.sequenceontology.org/).本体已针对几个生物学领域进行了扩展和提炼,并对本体的结构进行了改进。为了提高其公共信息库提供的基因产品注释的数量和质量,GO联盟发起了一项重点工作,为包括人类和几个关键模式生物在内的许多“参考”基因组提供全面和详细的同源基因注释。软件开发包括本体编辑工具OBO-编辑的两个版本,以及对Amigo浏览器界面的改进。
The Gene Ontology (GO) project (http://www.geneontology.org/) provides a set of structured, controlled vocabularies for community use in annotating genes, gene products and sequences (also see http://www.sequenceontology.org/). The ontologies have been extended and refined for several biological areas, and improvements to the structure of the ontologies have been implemented. To improve the quantity and quality of gene product annotations available from its public repository, the GO Consortium has launched a focused effort to provide comprehensive and detailed annotation of orthologous genes across a number of ‘reference’ genomes, including human and several key model organisms. Software developments include two releases of the ontology-editing tool OBO-Edit, and improvements to the AmiGO browser interface.
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