IMI 2021 Yearly Digest.

IMI 2021 Yearly Digest.
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IMI 2021年度文摘

DOI:
10.1167/iovs.62.5.7
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发表时间:
2021-04-28
影响因子:
4.4
通讯作者:
Smith EL 3rd
Smith EL 3rd
中科院分区:
医学2区
文献类型:
--
作者:
Jong M;Jonas JB;Wolffsohn JS;Berntsen DA;Cho P;Clarkson-Townsend D;Flitcroft DI;Gifford KL;Haarman AEG;Pardue MT;Richdale K;Sankaridurg P;Tedja MS;Wildsoet CF;Bailey-Wilson JE;Guggenheim JA;Hammond CJ;Kaprio J;MacGregor S;Mackey DA;Musolf AM;Klaver CCW;Verhoeven VJM;Vitart V;Smith EL 3rd

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国际近视研究所(IMI)年度文摘重点介绍了自第一批IMI白皮书发布以来被认为具有重要意义的新研究。 对2019年至2020年年中期间有关近视的文章进行了文献检索,为定义和分类、实验模型、遗传学、干预措施、临床试验以及临床管理提供信息。同时也考虑了同一时期主要会议的会议摘要。 2019年至2020年年中期间发表了1000篇关于近视的文章。主要进展包括在目前正在进行的测试近视干预措施的研究中使用了近视前期的定义,病理性近视领域的新定义,新的药物治疗在实验模型中的作用(如降低眼压的拉坦前列素),对屈光不正进行的一项大型荟萃分析确定了336个新的基因位点,新的临床干预措施(如离焦多焦点眼镜以及低剂量阿托品与角膜塑形术(OK)的联合治疗),屈光不正的规范标准,在确定近视控制治疗方法时安慰剂对照组的伦理困境,报告近视降低的实际度量而非百分比降低,比较儿童佩戴角膜塑形镜的风险与近视导致视力损害的风险,预防近视和眼轴长度增加与生活质量的合理性,以及未来视力丧失的情况。 自2019年IMI白皮书发布以来,已经发表了大量关于近视的研究。年度文摘旨在突出近视方面的最新研究和进展。
The International Myopia Institute (IMI) Yearly Digest highlights new research considered to be of importance since the publication of the first series of IMI white papers. A literature search was conducted for articles on myopia between 2019 and mid-2020 to inform definitions and classifications, experimental models, genetics, interventions, clinical trials, and clinical management. Conference abstracts from key meetings in the same period were also considered. One thousand articles on myopia have been published between 2019 and mid-2020. Key advances include the use of the definition of premyopia in studies currently under way to test interventions in myopia, new definitions in the field of pathologic myopia, the role of new pharmacologic treatments in experimental models such as intraocular pressure–lowering latanoprost, a large meta-analysis of refractive error identifying 336 new genetic loci, new clinical interventions such as the defocus incorporated multisegment spectacles and combination therapy with low-dose atropine and orthokeratology (OK), normative standards in refractive error, the ethical dilemma of a placebo control group when myopia control treatments are established, reporting the physical metric of myopia reduction versus a percentage reduction, comparison of the risk of pediatric OK wear with risk of vision impairment in myopia, the justification of preventing myopic and axial length increase versus quality of life, and future vision loss. Large amounts of research in myopia have been published since the IMI 2019 white papers were released. The yearly digest serves to highlight the latest research and advances in myopia.
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