Health-Related Quality-of-Life Outcomes of Very Preterm or Very Low Birth Weight Adults: Evidence From an Individual Participant Data Meta-Analysis.
Health-Related Quality-of-Life Outcomes of Very Preterm or Very Low Birth Weight Adults: Evidence From an Individual Participant Data Meta-Analysis.
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DOI：
10.1007/s40273-022-01201-2
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发表时间：
2023-01
影响因子：
4.4
通讯作者：
Petrou, Stavros
中科院分区：
文献类型：
--
作者：
Bolbocean, Corneliu;van der Pal, Sylvia;van Buuren, Stef;Anderson, Peter J.;Bartmann, Peter;Baumann, Nicole;Cheong, Jeanie L. Y.;Darlow, Brian A.;Doyle, Lex W.;Evensen, Kari Anne, I;Horwood, John;Indredavik, Marit S.;Johnson, Samantha;Marlow, Neil;Mendonca, Marina;Ni, Yanyan;Wolke, Dieter;Woodward, Lianne;Verrips, Erik;Petrou, Stavros
对早产儿和/或低出生体重儿(VP/VLBW)的健康相关生活质量的评估在生物医学评估的同时提供了有价值的补充信息。然而，VP/VLBW状态对成年后健康相关生活质量的影响尚不确定。这项研究的目的是检验VP/VLBW状态与成年早期基于偏好的健康相关生活质量结果之间的关系。个体参与者的数据来自五个预期的队列，包括出生于VP/VLBW的个体和为“欧洲早产儿童和成人出生研究”联盟做出贡献的对照组。合并的数据集包括超过2100名成年VP/VLBW幸存者，年龄范围为18-29岁。主要接触者为孕32周前出生(VP)和/或出生体重<1500 g(VLBW)。结果测量包括由卫生实用程序指数Mark 3和缩写6D生成的多属性实用程序分数。数据分析采用广义线性混合模型，一步法使用固定效应和随机效应模型。与足月出生或正常出生体重相比，VP/VLBW状态与健康实用工具指数MARK3多属性效用得分− 0.06(95%可信区间− 0.08，− 0.04)有显著差异；这一点在简式6D中没有重复。受影响的功能区包括视觉、行走、灵巧和认知。VP/VLBW状态与较差的情绪或社会功能或增加的疼痛无关。VP/VLBW状态与成年早期的整体健康相关生活质量较低有关，特别是在身体和认知功能方面。需要进一步的研究来评估VP/VLBW状态对成年中后期健康相关生活质量结果的影响。网上版载有补充材料，可在10.1007/s40273-022-01201-2查阅。
Assessment of health-related quality of life for individuals born very preterm and/or low birthweight (VP/VLBW) offers valuable complementary information alongside biomedical assessments. However, the impact of VP/VLBW status on health-related quality of life in adulthood is inconclusive. The objective of this study was to examine associations between VP/VLBW status and preference-based health-related quality-of-life outcomes in early adulthood. Individual participant data were obtained from five prospective cohorts of individuals born VP/VLBW and controls contributing to the ‘Research on European Children and Adults Born Preterm’ Consortium. The combined dataset included over 2100 adult VP/VLBW survivors with an age range of 18–29 years. The main exposure was defined as birth before 32 weeks’ gestation (VP) and/or birth weight below 1500 g (VLBW). Outcome measures included multi-attribute utility scores generated by the Health Utilities Index Mark 3 and the Short Form 6D. Data were analysed using generalised linear mixed models in a one-step approach using fixed-effects and random-effects models. VP/VLBW status was associated with a significant difference in the Health Utilities Index Mark 3 multi-attribute utility score of − 0.06 (95% confidence interval − 0.08, − 0.04) in comparison to birth at term or at normal birthweight; this was not replicated for the Short Form 6D. Impacted functional domains included vision, ambulation, dexterity and cognition. VP/VLBW status was not associated with poorer emotional or social functioning, or increased pain. VP/VLBW status is associated with lower overall health-related quality of life in early adulthood, particularly in terms of physical and cognitive functioning. Further studies that estimate the effects of VP/VLBW status on health-related quality-of-life outcomes in mid and late adulthood are needed. The online version contains supplementary material available at 10.1007/s40273-022-01201-2.
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影响因子：
2.9
作者：
Beam, Andrew L.;Fried, Inbar;Armstrong, Joanne
通讯作者：
Armstrong, Joanne
影响因子：
15.1
作者：
Anderson PJ;de Miranda DM;Albuquerque MR;Indredavik MS;Evensen KAI;Van Lieshout R;Saigal S;Taylor HG;Raikkonen K;Kajantie E;Marlow N;Johnson S;Woodward LJ;Austin N;Nosarti C;Jaekel J;Wolke D;Cheong JL;Burnett A;Treyvaud K;Lee KJ;Doyle LW
通讯作者：
Doyle LW
影响因子：
4
作者：
Horvath H;Brindis CD;Reyes EM;Yamey G;Franck L;Knowledge Transfer and Exchange (KTE) Working Group
通讯作者：
Knowledge Transfer and Exchange (KTE) Working Group
DOI：
10.1631/jzus.2005.b0936
发表时间：
2005-09-01
期刊：
Journal of Zhejiang University. Science. B
影响因子：
--
作者：
Chen, Tian-Hui;Li, Lu;Kochen, Michael M
通讯作者：
Kochen, Michael M
影响因子：
3.8
作者：
Batsvik, Berit;Vederhus, Bente J.;Markestad, Trond
通讯作者：
Markestad, Trond