Review of Diagnostic Biomarkers in Autoimmune Pancreatitis: Where Are We Now?

Review of Diagnostic Biomarkers in Autoimmune Pancreatitis: Where Are We Now?
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DOI:
10.3390/diagnostics11050770
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发表时间:
2021-04-25
期刊:
Diagnostics (Basel, Switzerland)
影响因子:
--
通讯作者:
Kodama Y
Kodama Y
中科院分区:
其他
文献类型:
--
作者:
Yokode M;Shiokawa M;Kodama Y

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自身免疫性胰腺炎(AIP)是IgG 4相关疾病(IgG 4-RD)的胰腺表现。AIP缺乏疾病特异性生物标志物,因此,很难区分AIP与恶性肿瘤,特别是胰腺癌。本文综述了近年来AIP潜在诊断生物标志物的研究进展。已经进行了许多研究,但没有确定AIP的特异性生物标志物。因此,需要进一步的研究来确定AIP的准确诊断生物标志物。
Autoimmune pancreatitis (AIP) is a pancreatic manifestation of an IgG4-related disease (IgG4-RD). AIP lacks disease-specific biomarkers, and therefore, it is difficult to distinguish AIP from malignancies, especially pancreatic cancer. In this review, we have summarized the latest findings on potential diagnostic biomarkers for AIP. Many investigations have been conducted, but no specific biomarkers for AIP are identified. Therefore, further studies are required to identify accurate diagnostic biomarkers for AIP.
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