A Viability Analysis of Tumor-Bearing Frozen Autograft for the Reconstruction After Resection of Malignant Bone Tumors Using 99mTc-MDP Scintigraphy

A Viability Analysis of Tumor-Bearing Frozen Autograft for the Reconstruction After Resection of Malignant Bone Tumors Using 99mTc-MDP Scintigraphy
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使用 99mTc-MDP 闪烁扫描技术进行恶性骨肿瘤切除后重建的带肿瘤冷冻自体移植物的可行性分析

DOI:
10.1097/rlu.0000000000004436
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发表时间:
2022
影响因子:
10.6
通讯作者:
Tsuchiya Hiroyuki
Tsuchiya Hiroyuki
中科院分区:
医学3区
文献类型:
--
作者:
Araki Yoshihiro;Yamamoto Norio;Hayashi Katsuhiro;Takeuchi Akihiko;Miwa Shinji;Igarashi Kentaro;Higuchi Takashi;Abe Kensaku;Taniguchi Yuta;Yonezawa Hirotaka;Morinaga Sei;Asano Yohei;Nojima Takayuki;Taki Junichi;Tsuchiya Hiroyuki

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结果术后60个月,95%~97%的患者示踪剂摄取正常率为95%~97%,与自由冷冻组相比,椎弓根冷冻组中段和周边区的摄取正常率较低(均P=0.03)。骨折和骨不连与低摄取率相关,而感染与事件发生前高摄取率相关。结论99mTC-MDP显像计算摄取率是一种客观、准确的评价方法。椎弓根冻存骨的示踪剂摄取正常化时间明显早于游离冻存骨。术后并发症也是可以预测的。
ResultsNormalization of tracer uptake was achieved in 95% to 97% of the cases by 60 months postoperatively, and earlier in the middle zone and peripheral zone in the pedicle freezing group in comparison to the free freezing group (both P= 0.03). Fracture and nonunion was associated with a low uptake ratio, whereas infection was associated with a high uptake ratio before the occurrence of the event.ConclusionsThe calculation of the uptake ratio using 99m Tc-MDP scans was an objective and accurate evaluation method. The period to normalization of tracer uptake in the pedicle frozen bone was significantly earlier than that in the free frozen bone. The postoperative complications can be also predicted.
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