Influenza pandemics of the 20th century.

Influenza pandemics of the 20th century.
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DOI:
10.3201/eid1201.051254
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发表时间:
2006-01
影响因子:
11.8
通讯作者:
Kilbourne ED
Kilbourne ED
中科院分区:
医学2区
文献类型:
--
作者:
Kilbourne ED

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甲型流感病毒感染在区分真正的流行病、假流行病和流行病方面造成了混乱。世纪发生了三次全球性流感大流行:1918年、1957年和1968年。后两个是在现代病毒学的时代和最彻底的特点。所有这3种流感都已被非正式地确定为西班牙流感、亚洲流感和香港流感。目前已知它们分别代表甲型流感病毒的3种不同抗原亚型:H1N1、H2N2和H3N2。没有被归类为真正的大流行病的是3个值得注意的流行病:1947年的假流行病,死亡率很低,1977年的流行病是儿童大流行病,1976年的猪流感流行病被认为具有大流行的潜力。重大流感流行没有可预测的周期或模式,而且各不相同。有证据表明,血凝素亚型发生变化的真正大流行是由动物甲型流感病毒的基因重组引起的。
Influenza A virus infection created confusion in distinguishing true pandemics, pseudopandemics, and epidemics. Three worldwide (pandemic) outbreaks of influenza occurred in the 20th century: in 1918, 1957, and 1968. The latter 2 were in the era of modern virology and most thoroughly characterized. All 3 have been informally identified by their presumed sites of origin as Spanish, Asian, and Hong Kong influenza, respectively. They are now known to represent 3 different antigenic subtypes of influenza A virus: H1N1, H2N2, and H3N2, respectively. Not classified as true pandemics are 3 notable epidemics: a pseudopandemic in 1947 with low death rates, an epidemic in 1977 that was a pandemic in children, and an abortive epidemic of swine influenza in 1976 that was feared to have pandemic potential. Major influenza epidemics show no predictable periodicity or pattern, and all differ from one another. Evidence suggests that true pandemics with changes in hemagglutinin subtypes arise from genetic reassortment with animal influenza A viruses.
DOI: 10.1056/nejm195809252591304
发表时间: 1958-01-01
影响因子: 158.5
作者:
MCCARROLL, JR;KILBOURNE, ED
通讯作者: KILBOURNE, ED
DOI: 10.2105/ajph.39.3.345
发表时间: 1949-01-01
影响因子: 12.7
作者:
SALK, JE;SURIANO, PC
通讯作者: SURIANO, PC
DOI: 10.1172/jci103789
发表时间: 1959-01-01
影响因子: 15.9
作者:
LOURIA, DB;BLUMENFELD, HL;ROGERS, DE
通讯作者: ROGERS, DE
DOI: 10.7326/0003-4819-33-2-371
发表时间: 1950-01-01
影响因子: 39.2
作者:
KILBOURNE, ED;LOGE, JP
通讯作者: LOGE, JP