Positive Lyme serology in subacute bacterial endocarditis. A study of four patients.

Positive Lyme serology in subacute bacterial endocarditis. A study of four patients.
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亚急性细菌性心内膜炎莱姆病血清学阳性。

DOI:
10.1001/jama.1990.03450220082027
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发表时间:
1990
期刊:
JAMA
影响因子:
--
通讯作者:
R. Dattwyler
R. Dattwyler
中科院分区:
--
文献类型:
--
作者:
A. Kaell;D. Volkman;P. Gorevic;R. Dattwyler

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相似文献

莱姆疏螺旋体病是一种由壁虱传播的伯氏疏螺旋体引起的多系统炎症性疾病。临床表现千变万化,累及皮肤、关节、周围和中枢神经系统以及心脏。然而,莱姆病的表现往往与其他疾病重叠。我们描述了来自莱姆病流行地区的四名患者,他们对伯氏杆菌的抗体水平升高,他们的体征和症状最初被归因于莱姆疏螺旋体病,但他们随后的血培养确定了非螺旋体亚急性细菌性心内膜炎的诊断。虽然四名患者中的三名患者的血清样本上的免疫印迹与之前感染伯氏杆菌的情况一致,但阳性的免疫印迹并不能确定是活动性感染。同样,伯氏杆菌的血清阳性仅表明可能接触到这种微生物。在存在其他疾病的情况下出现伯氏杆菌阳性血清可能会导致诊断混乱。
Lyme borreliosis is a multisystem inflammatory disorder caused by the tick-borne spirochete Borrelia burgdorferi. Clinical manifestations are protean, involving the skin, joints, peripheral and central nervous systems, and the heart. However, the presentation of Lyme disease often overlaps with that of other conditions. We describe four patients from a region endemic for Lyme disease who had elevated levels of antibodies reactive to B burgdorferi and whose signs and symptoms were initially attributed to Lyme borreliosis but whose subsequent blood cultures established a diagnosis of nonspirochetal subacute bacterial endocarditis. Although immunoblots on serum samples from three of the four patients were consistent with prior infection from B burgdorferi, a positive immunoblot does not establish active infection. Similarly, seropositivity to B burgdorferi only indicates possible exposure to this organism. The occurrence of positive serologies to B burgdorferi in the presence of other diseases can lead to diagnostic confusion.
莱姆病:起源于传染性,表现为风湿性。
DOI: --
发表时间: 1986
期刊: Advances in internal medicine
影响因子: --
作者:
Malawista,SE;Steere,AC
通讯作者: Steere,AC
DOI: 10.1093/infdis/157.4.790
发表时间: 1988-04-01
影响因子: 6.4
作者:
GRODZICKI, RL;STEERE, AC
通讯作者: STEERE, AC
DOI: 10.1002/art.1780310405
发表时间: 1988-04-01
影响因子: --
作者:
STEERE, AC;DURAY, PH;BUTCHER, EC
通讯作者: BUTCHER, EC
DOI: --
发表时间: 1985
期刊: The American journal of pathology
影响因子: --
作者:
Johnston,YE;Duray,PH;Steere,AC;Kashgarian,M;Buza,J;Malawista,SE;Askenase,PW
通讯作者: Askenase,PW
诊断早期莱姆病。
DOI: 10.1016/0002-9343(85)90432-2
发表时间: 1985
期刊: The American journal of medicine
影响因子: --
作者:
Shrestha,M;Grodzicki,RL;Steere,AC
通讯作者: Steere,AC