Epidemiology of COVID-19 in Mexico: Symptomatic profiles and presymptomatic people.
Epidemiology of COVID-19 in Mexico: Symptomatic profiles and presymptomatic people.
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DOI：
10.1016/j.ijid.2020.12.086
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发表时间：
2021-03
期刊：
影响因子：
--
通讯作者：
Alcántar-Fernández J
中科院分区：
文献类型：
--
作者：
Fernández-Rojas MA;Luna-Ruiz Esparza MA;Campos-Romero A;Calva-Espinosa DY;Moreno-Camacho JL;Langle-Martínez AP;García-Gil A;Solís-González CJ;Canizalez-Román A;León-Sicairos N;Alcántar-Fernández J
由于非特异性症状，COVID-19的诊断是困难和模糊的。此外，来自墨西哥的数据是基于好客人群的，没有体征和症状信息。因此，这项工作旨在提供有关墨西哥门诊患者COVID-19负担的流行病学信息，并确定可能有助于疾病早期诊断的症状性COVID-19特征。从6月到9月，在Salud Digna诊所收集了482，413名通过RT-PCR检测诊断为SARS-CoV-2的人的流行病学，临床和人口统计学数据。我们观察到SARS-CoV-2感染的发病率为41%，平均年龄为36岁，年轻人（20-40岁）受影响最大。在职业中，送货员（OR 1.38）或非正规贸易商（OR 1.33）的COVID-19风险较高。此外，13%的SARS-CoV-2感染发生在症状前患者中。最后，我们确定了与COVID-19相关的三种不同症状特征（常见、呼吸道和胃肠道）。SARS-CoV-2在门诊患者中的发病率很高，其中症状前携带者占很大比例，因此有必要增加检测并继续SARS-CoV-2监测，更好地描述体征和症状;在这方面，我们确定了三种有助于诊断COVID-19的症状特征。
The COVID-19 diagnosis is difficult and ambiguous due to nonspecific symptoms. Further, data from Mexico arehospitable population-based without signs and symptoms information. Thus, this work aims to provide epidemiology information about the burden of COVID-19 in Mexican outpatients and to identify symptomatic COVID-19 profiles that could help in the early diagnosis of the disease. From June to September, epidemiological, clinical, and demographic data of 482,413 individuals diagnosed by RT-PCR test for SARS-CoV-2 in Salud Digna clinics were collected. We observed a 41% incidence of SARS-CoV-2 infections with a mean age of 36 years and with young adults (20–40 years) being the most affected. Among occupations, delivery persons (OR 1.38) or informal traders (OR 1.33) had a higher risk of COVID-19. Moreover, 13% of SARS-CoV-2 infections were in presymptomatic patients. Finally, we identified three different symptomatic profiles (common, respiratory, and gastrointestinal) associated with COVID-19. The incidence of SARS-CoV-2 was high among outpatients with a significant proportion of presymptomatic carriers, and thus it is necessary to increase testing and continue SARS-CoV-2 surveillance with a better description of signs and symptoms; in this regard, we identified three symptomatic profiles that could help in the diagnosis of COVID-19.
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影响因子：
2.3
作者：
Basto-Abreu, Ana;Barrientos-Gutierrez, Tonatiuh;Villalpando, Salvador
通讯作者：
Villalpando, Salvador
DOI：
10.3138/jammi-2020-0030
发表时间：
2020-12-01
期刊：
Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada
影响因子：
--
作者：
Byambasuren, Oyungerel;Cardona, Magnolia;Glasziou, Paul
通讯作者：
Glasziou, Paul
影响因子：
51.1
作者：
Lee, Lennard Y. W.;Cozier, Jean-Baptiste;Kerr, Rachel
通讯作者：
Kerr, Rachel
影响因子：
8.4
作者：
Jung, Chan-Young;Park, Haeyong;Chang, Tae Ik
通讯作者：
Chang, Tae Ik
DOI：
10.11606/s1518-8787.2020054002643
发表时间：
2020-01-01
期刊：
Revista de Saúde Pública
影响因子：
--
作者：
Amorim Filho, Luiz;Szwarcwald, Célia Landmann;Werneck, Guilherme Loureiro
通讯作者：
Werneck, Guilherme Loureiro