Versatile use of bat ACE2 for cellular entry by MERS-CoV-like viruses.
Versatile use of bat ACE2 for cellular entry by MERS-CoV-like viruses.
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DOI:
10.1016/j.chom.2022.12.013
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发表时间:
2023-02-08
影响因子:
30.3
通讯作者:
Banerjee, Arinjay
中科院分区:
文献类型:
--
作者:
Baid, Kaushal;Banerjee, Arinjay
Cellular entry receptors for bat MERS-CoV-like viruses NeoCoV and PDF-2180 were unknown, leaving their zoonotic potential ambiguous. A recent study by Xiong et al. published in Nature identified bat ACE2 as the cellular entry receptor for both viruses, highlighting the ability of coronaviruses to utilize a range of entry receptors. Cellular entry receptors for bat MERS-CoV-like viruses NeoCoV and PDF-2180 were unknown, leaving their zoonotic potential ambiguous. A recent study by Xiong et al. published in Nature identified bat ACE2 as the cellular entry receptor for both viruses, highlighting the ability of coronaviruses to utilize a range of entry receptors.
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