Test-retest reliability of amygdala response to emotional faces.
Test-retest reliability of amygdala response to emotional faces.
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DOI：
10.1111/psyp.12129
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发表时间：
2013-11
期刊：
影响因子：
3.7
通讯作者：
Phan KL
中科院分区：
文献类型：
--
作者：
Sauder CL;Hajcak G;Angstadt M;Phan KL
在目前的研究中，我们使用情绪面孔匹配任务评估了杏仁核反应的重测信度，该任务已被广泛用于检查精神病人群的病理生理学和治疗机制。还检查了梭状面区（FFA）内的激活。27名健康志愿者在两个时间点（相隔约90天）完成了一项面部匹配范式的变异。杏仁核对恐惧面孔反应的重测信度估计值中等，而愤怒和快乐的信度较差。FFA的重测信度是中等到强，无论面部的影响。总的来说，这些发现表明杏仁核中BOLD MR信号的可靠性因面部情绪而异。努力提高测量精度，扩大样本量，或增加评估场合的数量似乎是必要的。
In the current study we evaluated the test-retest reliability of amygdala response using an emotional face-matching task that has been widely usedto examine pathophysiology and treatment mechanisms in psychiatric populations. Activation within the fusiform face area (FFA) was also examined. Twenty-sevenhealthy volunteers completed a variation of the face-matching paradigm developed by at two time-points approximately 90 days apart. Estimates of test-retest reliability of amygdala response to fearful faces were moderate, whereas angry and happy showed poor reliability. Test-retest reliability of the FFA was moderate to strong, regardless of facial affect. Collectively, these findings indicate that the reliability of the BOLD MR signal in the amygdala varies substantiallyby facial affect. Efforts to improve measurement precision, enlarge sample sizes, or increase the number of assessment occasions seem warranted.
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