Risk factors for house-entry by malaria vectors in a rural town and satellite villages in The Gambia.
Risk factors for house-entry by malaria vectors in a rural town and satellite villages in The Gambia.
复制标题
疟疾媒介在农村小镇和冈比亚卫星村庄的居住风险因素。
DOI：
10.1186/1475-2875-7-2
复制
发表时间：
2008-01-07
期刊：
影响因子：
3
通讯作者：
Lindsay, Steven W.
中科院分区：
文献类型：
--
作者：
Kirby, Matthew J.;Green, Clare;Milligan, Paul M.;Sismanidis, Charalambos;Jasseh, Momadou;Conway, David J.;Lindsay, Steven W.
在干预前一年的一项随机对照试验，调查家庭筛查对疟疾传播媒介的保护作用，多因素风险因素分析研究，以确定影响蚊子进入房屋的因素。在冈比亚的疟疾传播季节，在法拉芬尼镇和周围村庄的976所房屋中使用CDC灯光陷阱对蚊子进行采样，每一个晚上。从个别房子的渔获量都（a）左未调整和（B）调整相对于在四个哨兵的房子，在整个期间每晚操作，以允许夜间夜间变化捕获的蚊子数量。住房的特点是地点、建筑、人的居住情况及其控制蚊子的活动，以及大院内家畜的数量和种类。捕获了106 536只蚊子，其中55%是广义冈比亚按蚊，这是该地区的主要疟疾病媒。有七倍以上的安。冈比亚公司在那些村庄（几何平均值/陷阱夜= 43.7，95%置信区间，CI = 39.5-48.4）比在法拉芬尼镇（6.3，5.7-7.2）和显著变化之间的住宅区（p < 0.001）。负二项多变量模型使用未调整或调整陷阱数据同样表现良好。使用未经调整的数据，如果房屋位于城镇，（OR = 0.11，95%CI = 0.09-0.13），屋檐关闭（OR = 0.71，0.60-0.85），在房屋附近拴马（OR = 0.77，0.73-0.82），夜间在房间内点香（OR = 0.56，0.47-0.66）。室内（OR = 1.04，1.02-1.06）、诱捕室（OR = 1.19，1.13-1.25）和泥砖墙与混凝土墙相比（OR = 1.44，1.10-1.87），每增加一人，蚊子数量增加。这项研究表明，疟疾传播的风险在农村地区最大，那里有大量的人睡在用土砖砌成的房子里，屋檐是敞开的，马不在附近拴着，晚上也不烧柴。在设计和分析旨在减少冈比亚和撒哈拉以南非洲其他地区疟疾传播的干预研究时，需要考虑这些因素。
In the pre-intervention year of a randomized controlled trial investigating the protective effects of house screening against malaria-transmitting vectors, a multi-factorial risk factor analysis study was used to identify factors that influence mosquito house entry. Mosquitoes were sampled using CDC light traps in 976 houses, each on one night, in Farafenni town and surrounding villages during the malaria-transmission season in The Gambia. Catches from individual houses were both (a) left unadjusted and (b) adjusted relative to the number of mosquitoes caught in four sentinel houses that were operated nightly throughout the period, to allow for night-to-night variation. Houses were characterized by location, architecture, human occupancy and their mosquito control activities, and the number and type of domestic animals within the compound. 106,536 mosquitoes were caught, of which 55% were Anopheles gambiae sensu lato, the major malaria vectors in the region. There were seven fold higher numbers of An. gambiae s.l. in the villages (geometric mean per trap night = 43.7, 95% confidence intervals, CIs = 39.5–48.4) than in Farafenni town (6.3, 5.7–7.2) and significant variation between residential blocks (p < 0.001). A negative binomial multivariate model performed equally well using unadjusted or adjusted trap data. Using the unadjusted data the presence of nuisance mosquitoes was reduced if the house was located in the town (odds ratio, OR = 0.11, 95% CIs = 0.09–0.13), the eaves were closed (OR = 0.71, 0.60–0.85), a horse was tethered near the house (OR = 0.77, 0.73–0.82), and churai, a local incense, was burned in the room at night (OR = 0.56, 0.47–0.66). Mosquito numbers increased per additional person in the house (OR = 1.04, 1.02–1.06) or trapping room (OR = 1.19, 1.13–1.25) and when the walls were made of mud blocks compared with concrete (OR = 1.44, 1.10–1.87). This study demonstrates that the risk of malaria transmission is greatest in rural areas, where large numbers of people sleep in houses made of mud blocks, where the eaves are open, horses are not tethered nearby and where churai is not burnt at night. These factors need to be considered in the design and analysis of intervention studies designed to reduce malaria transmission in The Gambia and other parts of sub-Saharan Africa.
登录
查看更多内容
DOI：
10.1016/j.trstmh.2003.11.005
发表时间：
2004-07-01
影响因子：
2.2
作者：
Balls, MJ;Bodker, R;Lindsay, SW
通讯作者：
Lindsay, SW
影响因子：
2.1
作者：
Bogh, C;Clarke, SE;Lindsay, SW
通讯作者：
Lindsay, SW
DOI：
10.1016/0035-9203(95)90406-9
发表时间：
1995-11-01
影响因子：
2.2
作者：
Knols, BGJ;deJong, R;Takken, W
通讯作者：
Takken, W
影响因子：
2.1
作者：
Lemasson, JJ;Fontenille, D;Molez, JF
通讯作者：
Molez, JF
影响因子：
1.9
作者：
LINDSAY, SW;ARMSTRONG, JRM;WILKINS, HA
通讯作者：
WILKINS, HA