Bioindicators in the MIDUS national study: protocol, measures, sample, and comparative context.

Bioindicators in the MIDUS national study: protocol, measures, sample, and comparative context.
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DOI:
10.1177/0898264310374355
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发表时间:
2010-12
影响因子:
2.8
通讯作者:
Ryff CD
Ryff CD
中科院分区:
医学3区
文献类型:
--
作者:
Dienberg Love G;Seeman TE;Weinstein M;Ryff CD

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MIDUS是一项针对25至74岁基线(1995/ 1996年)个人健康和老龄化的全国性研究。纵向调查评估(2004/05),随后对35-85岁的子样本进行生物学评估。为了便于公众使用,我们描述了方案、措施和样本。受访者前往诊所进行为期两天的数据收集,包括空腹血液标本、12小时尿液标本、病史、体格检查、骨密度测定、实验室挑战(心率变异性、血压、呼吸、唾液皮质醇)。生物方案的应答率(N = 1255)分别为39.3%和43.1%(对无法定位或联系的患者进行调整)。不参加的原因是旅行、家庭责任和太忙。答复者在大多数人口特征和健康评估方面与招聘人员相当。该议定书相对-à-vis其他类似研究的优势包括有机会将生物因素与其他MIDUS项目的不同内容联系起来。
MIDUS is a national study of health and aging among individuals aged 25 to 74 at baseline(1995/96). Longitudinal survey assessments (2004/05), were followed by biological assessments on a subsample aged 35–85. To facilitate public use, we describe the protocol, measures, and sample. Respondents traveled to clinics for a two-day data collection protocol that included fasting blood specimens, 12-hour urine specimen, medical history, physical exam, bone densitometry, a laboratory challenge (heart rate variability, blood pressure, respiration, salivary cortisol). Response rates for the biological protocol (N = 1,255) were 39.3%, or 43.1% (adjusting for those who could not be located or contacted). Reasons for non-participation were travel, family obligations, and being too busy. Respondents were comparable to the recruitment pool on most demographic characteristics and health assessments. Strengths of the protocol vis-à-vis other similar studies include opportunities to link biological factors with diverse content from other MIDUS projects.
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