Children's psychological distress during pediatric HSCT: parent and child perspectives.
Children's psychological distress during pediatric HSCT: parent and child perspectives.
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DOI：
10.1002/pbc.23185
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发表时间：
2012-02
影响因子：
3.2
通讯作者：
Parsons, Susan K.
中科院分区：
文献类型：
--
作者：
Chang, Grace;Ratichek, Sara J.;Recklitis, Christopher;Syrjala, Karen;Patel, Sunita K.;Harris, Lynnette;Rodday, Angie Mae;Tighiouart, Hocine;Parsons, Susan K.
造血干细胞移植（HSCT）可能是具有挑战性的儿科受体和他们的家庭。人们对接受治疗者在开始治疗时和治疗后一年的心理状态知之甚少。本研究的目的是从父母的角度描述107名儿童HSCT受者的心理状态，并比较55名儿童的父母和孩子的报告。我们假设父母和孩子对儿童痛苦的报告之间存在差异。在HSCT前一个月和后一年完成DSM-IV-TR，儿童版（child - scid）结构化临床访谈模块的符合条件的儿童参与者及其父母的多站点前瞻性研究。诊断为阈值或亚阈值。根据家长的说法，近30%的孩子在移植前后都有焦虑症；其中约有一半符合阈值标准。父母和孩子在焦虑障碍方面的一致性在基线时较差（κ= - 0.18, 95% CI= - 0.33, - 0.02），在12个月时尚可（κ= 0.31, 95% CI= - 0.04, 0.66）。基线时情绪障碍的一致性一般（10%患病率，κ=0.39, 95% CI= - 0.02, 0.79）， 12个月时一致性中等（14%患病率，κ=0.41, 95% CI= 0.02, 0.80）。焦虑（30%）和情绪（10 - 14%）症状在移植前后的儿童中都很常见；父母和孩子对这些症状的报告不一致。建议父母和儿童提供意见，以便更准确地确定在造血干细胞移植期间和之后可能需要额外干预的儿童。
Hematopoietic stem cell transplantation (HSCT) can be challenging to pediatric recipients and their families. Little is known about the recipients' psychological status as they initiate treatment and in the year afterwards. The purpose of this study is to describe the psychological status of 107 pediatric HSCT recipients from their parents' perspective, and to compare reports from parents and children in a subset of 55 children. We hypothesized that there would be discrepancies between parent and child report of child distress. Multi-site, prospective study of eligible child participants and their parents who completed selected modules from the Structured Clinical Interview for DSM-IV-TR, Childhood Version (KID-SCID) the month before and one year after HSCT. Diagnoses were threshold or subthreshold. According to parents, nearly 30% of children had anxiety disorder_both before and after HSCT; approximately half of these met threshold criteria. Agreement between parents and children for anxiety disorders was poor at baseline (κ= −0.18, 95th % CI= −0.33, −0.02) and fair at 12 months (κ= 0.31, 95th % CI= −0.04, 0.66). Agreement about mood disorders was fair at baseline (10% prevalence, κ=0.39, 95th % CI=−0.02, 0.79) and moderate at 12 months (14% prevalence, κ=0.41, 95th % CI= 0.02, 0.80). Anxiety (30%) and mood (10 to 14%) symptoms are common in children both before and after HSCT; parent and child reports of these symptoms do not agree. Input from parents and children is recommended to identify more accurately children who may need additional intervention during and following HSCT.
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影响因子：
7.3
作者：
Backenstrass, M;Frank, A;Kronmüller, KT
通讯作者：
Kronmüller, KT
影响因子：
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10.1016/j.chc.2010.01.009
发表时间：
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影响因子：
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通讯作者：
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