DBTSS provides a tissue specific dynamic view of Transcription Start Sites.
DBTSS provides a tissue specific dynamic view of Transcription Start Sites.
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DBTSS提供了转录起始位点的组织特定动态视图。
DOI：
10.1093/nar/gkp1017
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发表时间：
2010-01
影响因子：
14.9
通讯作者：
Nakai K
中科院分区：
文献类型：
--
作者：
Yamashita R;Wakaguri H;Sugano S;Suzuki Y;Nakai K
转录起始位点数据库（DBTSS）是一个包含真核生物mRNA转录起始位点（TSS）精确位置信息的数据库。在这次更新中，我们包括了3.3亿个新标签，这些标签是通过对人类和小鼠中oligo-cap选择的cDNA的5′端进行大规模测序而产生的。标签收集自正常胎儿或成人组织，包括脑、胸腺、肝、肾和心脏，来自21种不同生长条件下的6种人细胞系以及小鼠NIH 3 T3细胞系：总共代表31种不同的细胞类型或培养条件。这种前所未有的数据深度增加现在使DBTSS能够忠实地代表TSS在不同细胞类型和条件下，在发育和进化过程中动态变化的景观。可以在一系列新界面中查看不同细胞类型和条件下替代5′-末端的差异使用。启动子序列信息现在显示在比较基因组学查看器中，其中可以评估TSS的进化周转。DBTSS可以在http://dbtss.hgc.jp/上访问。
DataBase of Transcription Start Sites (DBTSS) is a database which contains precise positional information for transcription start sites (TSSs) of eukaryotic mRNAs. In this update, we included 330 million new tags generated by massively sequencing the 5′-end of oligo-cap selected cDNAs in humans and mice. The tags were collected from normal fetal or adult human tissues, including brain, thymus, liver, kidney and heart, from 6 human cell lines in 21 diverse growth conditions as well as from mouse NIH3T3 cell line: altogether 31 different cell types or culture conditions are represented. This unprecedented increase in depth of data now allows DBTSS to faithfully represent the dynamically changing landscape of TSSs in different cell types and conditions, during development and in the course of evolution. Differential usage of alternative 5′-ends across cell types and conditions can be viewed in a series of new interfaces. Promoter sequence information is now displayed in a comparative genomics viewer where evolutionary turnover of the TSSs can be evaluated. DBTSS can be accessed at http://dbtss.hgc.jp/.
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影响因子：
56.9
作者：
Carninci, P;Kasukawa, T;Hayashizaki, Y
通讯作者：
Hayashizaki, Y
DOI：
10.1038/nrg2636
发表时间：
2009-09
期刊：
Nature reviews. Genetics
影响因子：
--
作者：
通讯作者：
--
影响因子：
14.9
作者：
Tsuchihara K;Suzuki Y;Wakaguri H;Irie T;Tanimoto K;Hashimoto S;Matsushima K;Mizushima-Sugano J;Yamashita R;Nakai K;Bentley D;Esumi H;Sugano S
通讯作者：
Sugano S
影响因子：
64.8
作者：
Bentley DR;Balasubramanian S;Swerdlow HP;Smith GP;Milton J;Brown CG;Hall KP;Evers DJ;Barnes CL;Bignell HR;Boutell JM;Bryant J;Carter RJ;Keira Cheetham R;Cox AJ;Ellis DJ;Flatbush MR;Gormley NA;Humphray SJ;Irving LJ;Karbelashvili MS;Kirk SM;Li H;Liu X;Maisinger KS;Murray LJ;Obradovic B;Ost T;Parkinson ML;Pratt MR;Rasolonjatovo IM;Reed MT;Rigatti R;Rodighiero C;Ross MT;Sabot A;Sankar SV;Scally A;Schroth GP;Smith ME;Smith VP;Spiridou A;Torrance PE;Tzonev SS;Vermaas EH;Walter K;Wu X;Zhang L;Alam MD;Anastasi C;Aniebo IC;Bailey DM;Bancarz IR;Banerjee S;Barbour SG;Baybayan PA;Benoit VA;Benson KF;Bevis C;Black PJ;Boodhun A;Brennan JS;Bridgham JA;Brown RC;Brown AA;Buermann DH;Bundu AA;Burrows JC;Carter NP;Castillo N;Chiara E Catenazzi M;Chang S;Neil Cooley R;Crake NR;Dada OO;Diakoumakos KD;Dominguez-Fernandez B;Earnshaw DJ;Egbujor UC;Elmore DW;Etchin SS;Ewan MR;Fedurco M;Fraser LJ;Fuentes Fajardo KV;Scott Furey W;George D;Gietzen KJ;Goddard CP;Golda GS;Granieri PA;Green DE;Gustafson DL;Hansen NF;Harnish K;Haudenschild CD;Heyer NI;Hims MM;Ho JT;Horgan AM;Hoschler K;Hurwitz S;Ivanov DV;Johnson MQ;James T;Huw Jones TA;Kang GD;Kerelska TH;Kersey AD;Khrebtukova I;Kindwall AP;Kingsbury Z;Kokko-Gonzales PI;Kumar A;Laurent MA;Lawley CT;Lee SE;Lee X;Liao AK;Loch JA;Lok M;Luo S;Mammen RM;Martin JW;McCauley PG;McNitt P;Mehta P;Moon KW;Mullens JW;Newington T;Ning Z;Ling Ng B;Novo SM;O'Neill MJ;Osborne MA;Osnowski A;Ostadan O;Paraschos LL;Pickering L;Pike AC;Pike AC;Chris Pinkard D;Pliskin DP;Podhasky J;Quijano VJ;Raczy C;Rae VH;Rawlings SR;Chiva Rodriguez A;Roe PM;Rogers J;Rogert Bacigalupo MC;Romanov N;Romieu A;Roth RK;Rourke NJ;Ruediger ST;Rusman E;Sanches-Kuiper RM;Schenker MR;Seoane JM;Shaw RJ;Shiver MK;Short SW;Sizto NL;Sluis JP;Smith MA;Ernest Sohna Sohna J;Spence EJ;Stevens K;Sutton N;Szajkowski L;Tregidgo CL;Turcatti G;Vandevondele S;Verhovsky Y;Virk SM;Wakelin S;Walcott GC;Wang J;Worsley GJ;Yan J;Yau L;Zuerlein M;Rogers J;Mullikin JC;Hurles ME;McCooke NJ;West JS;Oaks FL;Lundberg PL;Klenerman D;Durbin R;Smith AJ
通讯作者：
Smith AJ
DBTSS：转录起始站点数据库，2008年进度报告。
影响因子：
14.9
作者：
Wakaguri H;Yamashita R;Suzuki Y;Sugano S;Nakai K
通讯作者：
Nakai K