Laboratory-based x-ray dark-field microscopy

Laboratory-based x-ray dark-field microscopy
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基于实验室的 X 射线暗视野显微镜

DOI:
10.1103/physrevapplied.20.064039
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发表时间:
2023
影响因子:
4.6
通讯作者:
Esposito M
Esposito M
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
Esposito M

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我们证明了实验室为基础的X射线显微镜的能力,使用强度调制掩模,访问在暗场对比度通道的亚微米长度尺度,同时保持微米分辨率的解决(折射和衰减)通道。暗场对比度通道揭示了低于系统分辨率的样本特征集合的存在。分辨折射和衰减通道提供多模态高分辨率成像,低至微米级。我们调查制度的调制和未调制的暗场以及折射,量化它们的依赖关系的特征尺寸在成像对象和孔径大小的强度调制掩模之间的关系。我们提出了一个分析模型,将测量信号与样品的微观特性联系起来。最后,我们展示了显微暗场对比通道在生命科学和物理科学应用中的相关性,为软骨中的胶原束成像和锂电池中的树突状生长提供了概念验证结果。
We demonstrate the capability of laboratory-based x-ray microscopes, using intensity-modulation masks, to access the submicron length scale in the dark-field contrast channel while maintaining micron resolution in the resolved (refraction and attenuation) channels. The dark-field contrast channel reveals the presence of ensembles of samples’ features below the system resolution. Resolved refraction and attenuation channels provide multimodal high-resolution imaging down to the micron scale. We investigate the regimes of modulated and unmodulated dark field as well as refraction, quantifying their dependence on the relationship between feature size in the imaged object and aperture size in the intensity-modulation mask. We propose an analytical model to link the measured signal with the sample’s microscopic properties. Finally, we demonstrate the relevance of the microscopic dark-field contrast channel in applications from both the life and physical sciences, providing proof-of-concept results for imaging collagen bundles in cartilage and dendritic growth in lithium batteries.
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