Pancreas Cancer-Associated Pain Management.
Pancreas Cancer-Associated Pain Management.
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DOI：
10.1002/onco.13796
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发表时间：
2021-06
期刊：
影响因子：
--
通讯作者：
Precision Promise Consortium
中科院分区：
文献类型：
--
作者：
Coveler AL;Mizrahi J;Eastman B;Apisarnthanarax SJ;Dalal S;McNearney T;Pant S;Precision Promise Consortium
疼痛在胰腺癌患者中非常普遍，并导致疾病的发病率。疼痛可能是由于胰腺酶功能不全、梗阻和/或对腹腔神经丛中的神经产生直接的肿块效应。适当的支持护理以减少疼痛是这些患者整体管理的一个重要方面。关于胰腺癌引起的疼痛的具体治疗数据有限。在这里，我们回顾文献，并就可用于治疗这些患者的疼痛的多种方式提供建议。传播和采用这些最佳支持性护理实践可以改善胰腺癌患者的生活质量和数量。疼痛管理对于提高癌症患者的生活质量和生存是很重要的。胰腺癌疼痛的病理生理学是复杂的、多因素的。尽管肿瘤对化疗有反应，但相当大比例的患者面临着持续的癌症相关疼痛及其共同后果的风险。因此，胰腺癌患者的疼痛管理可能是具有挑战性的，通常需要多方面的方法。适当的支持护理以减轻疼痛是胰腺癌患者整体治疗的一个重要方面。这篇文章回顾了文献，并就可用于治疗这些患者的疼痛的多种方式提出了建议。
Pain is highly prevalent in patients with pancreas cancer and contributes to the morbidity of the disease. Pain may be due to pancreatic enzyme insufficiency, obstruction, and/or a direct mass effect on nerves in the celiac plexus. Proper supportive care to decrease pain is an important aspect of the overall management of these patients. There are limited data specific to the management of pain caused by pancreatic cancer. Here we review the literature and offer recommendations regarding multiple modalities available to treat pain in these patients. The dissemination and adoption of these best supportive care practices can improve quantity and quality of life for patients with pancreatic cancer. Pain management is important to improve the quality of life and survival of a patient with cancer. The pathophysiology of pain in pancreas cancer is complex and multifactorial. Despite tumor response to chemotherapy, a sizeable percentage of patients are at risk for ongoing cancer‐related pain and its comorbid consequences. Accordingly, the management of pain in patients with pancreas cancer can be challenging and often requires a multifaceted approach. Proper supportive care to decrease pain is an important aspect of the overall management of patients with pancreatic cancer. This article reviews the literature and offers recommendations regarding multiple modalities available to treat pain in these patients.
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DOI：
10.1155/2014/609594
发表时间：
2014
期刊：
Evidence-based complementary and alternative medicine : eCAM
影响因子：
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作者：
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DOI：
10.1200/edbk_100020
发表时间：
2019-01-01
期刊：
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
影响因子：
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Dalal, Shalini;Bruera, Eduardo
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