Metingear: a development environment for annotating genome-scale metabolic models.
Metingear: a development environment for annotating genome-scale metabolic models.
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DOI:
10.1093/bioinformatics/btt342
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发表时间:
2013-09-01
期刊:
影响因子:
--
通讯作者:
Steinbeck C
中科院分区:
文献类型:
--
作者:
May JW;James AG;Steinbeck C
Summary: Genome-scale metabolic models often lack annotations that would allow them to be used for further analysis. Previous efforts have focused on associating metabolites in the model with a cross reference, but this can be problematic if the reference is not freely available, multiple resources are used or the metabolite is added from a literature review. Associating each metabolite with chemical structure provides unambiguous identification of the components and a more detailed view of the metabolism. We have developed an open-source desktop application that simplifies the process of adding database cross references and chemical structures to genome-scale metabolic models. Annotated models can be exported to the Systems Biology Markup Language open interchange format. Availability: Source code, binaries, documentation and tutorials are freely available at http://johnmay.github.com/metingear. The application is implemented in Java with bundles available for MS Windows and Macintosh OS X. Contact: johnmay@ebi.ac.uk Supplementary information: Supplementary data are available at Bioinformatics online.
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影响因子:
14.9
作者:
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通讯作者:
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DOI:
10.1021/ci025584y
发表时间:
2003-03
期刊:
Journal of chemical information and computer sciences
影响因子:
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作者:
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作者:
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