Obesity, malnutrition, and trace element deficiency in the coronavirus disease (COVID-19) pandemic: An overview.
Obesity, malnutrition, and trace element deficiency in the coronavirus disease (COVID-19) pandemic: An overview.
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DOI：
10.1016/j.nut.2020.111016
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发表时间：
2021-01
期刊：
影响因子：
--
通讯作者：
Collo A
中科院分区：
文献类型：
--
作者：
Fedele D;De Francesco A;Riso S;Collo A
世界目前正面临冠状病毒病（COVID-19）大流行，它给医疗保健系统和工作人员带来巨大压力，通常呈现严重的临床特征，有时需要进入重症监护室。肥胖和营养不良导致的营养状况紊乱与急性疾病的临床结果相关。全身炎症、免疫系统损伤、肌肉减少症以及先前存在的相关疾病，例如与肥胖相关的呼吸系统、心血管和代谢疾病，可能是联系营养状况与 COVID-19 病程和结果的关键因素。然而，维生素和微量元素在调节免疫反应和炎症状态方面发挥着重要作用。总体而言，为了将量身定制的营养干预作为 COVID-19 患者治疗的一个组成部分，对患者营养状况的评估对于其易感性、病程、严重程度和对治疗的反应性的影响不可忽视。本研究的目的是回顾世界卫生组织宣布 COVID-19 为大流行后 3 个月内营养状况（包括微量元素和维生素状况）对疾病进程和结果影响的相关性的当前数据。
The world is currently facing the coronavirus disease (COVID-19) pandemic which places great pressure on health care systems and workers, often presents with severe clinical features, and sometimes requires admission into intensive care units. Derangements in nutritional status, both for obesity and malnutrition, are relevant for the clinical outcome in acute illness. Systemic inflammation, immune system impairment, sarcopenia, and preexisting associated conditions, such as respiratory, cardiovascular, and metabolic diseases related to obesity, could act as crucial factors linking nutritional status and the course and outcome of COVID-19. Nevertheless, vitamins and trace elements play an essential role in modulating immune response and inflammatory status. Overall, evaluation of the patient's nutritional status is not negligible for its implications on susceptibility, course, severity, and responsiveness to therapies, in order to perform a tailored nutritional intervention as an integral part of the treatment of patients with COVID-19. The aim of this study was to review the current data on the relevance of nutritional status, including trace elements and vitamin status, in influencing the course and outcome of the disease 3 mo after the World Health Organization's declaration of COVID-19 as a pandemic.
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DOI：
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发表时间：
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期刊：
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影响因子：
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影响因子：
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